Hep-Lock Side Effects
Generic name: heparin flush
Note: This document provides detailed information about Hep-Lock Side Effects associated with heparin flush. Some dosage forms listed on this page may not apply specifically to the brand name Hep-Lock.
Applies to heparin flush: intravenous solution.
Important warnings
This medicine can cause some serious health issues
Heparin flush should not be used to treat or prevent blood clots in the body. A separate heparin product is available to use for this purpose.
You should not use heparin flush if you have uncontrolled bleeding or a severe lack of platelets in your blood.
Heparin flush can cause bleeding. Call your doctor at once if you have easy bruising or unusual bleeding, such as a nosebleed, black or bloody tarry stools, or any bleeding that will not stop.
Tell your doctor about all medicines you use. This includes prescription, over-the-counter, vitamin, and herbal products. Using certain medicines while you are using heparin flush can cause you to bleed more easily.
Get emergency medical help if you have signs of an allergic reaction: nausea, vomiting, sweating, hives, itching, trouble breathing, swelling of your face, lips, tongue, or throat, or feeling like you might pass out.
Heparin flush can cause bleeding. Call your doctor at once if you have easy bruising or unusual bleeding, such as a nosebleed, black or bloody tarry stools, or any bleeding that will not stop.
Stop using heparin flush (the active ingredient contained in Hep-Lock) and call your doctor at once if you have:
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signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
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signs of a blood clot in the lung--chest pain, sudden cough, wheezing, rapid breathing, coughing up blood;
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signs of a blood clot in your leg--pain, swelling, warmth, or redness in one or both legs;
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a light-headed feeling, like you might pass out;
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skin changes in your arms, legs, hands, or feet; or
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(in an infant) extreme drowsiness, weakness, or gasping for breath.
Less serious side effects are more likely, and you may have none at all.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For healthcare professionals
Applies to heparin flush: intravenous kit, intravenous solution.
Hematologic
Hematologic side effects have included new thrombus formation in association with thrombocytopenia resulting from irreversible aggregation of platelets induced by heparin, the so-called "white clot syndrome". The process may lead to severe thromboembolic complications like skin necrosis, gangrene of the extremities that may lead to amputation, myocardial infarction, pulmonary embolism, stroke, and possibly death. Thrombocytopenia has been reported to occur in patients receiving heparin with a reported incidence of 0 to 30%.[Ref]
Hypersensitivity
Hypersensitivity side effects include the remote possibility of hypersensitivity reaction from the entry of extremely small subtherapeutic amounts of the heparin flush (the active ingredient contained in Hep-Lock) solution into the circulation. Such an occurrence has not been reported.[Ref]
References
1. (2009) "Product Information. Heparin Lock Flush (heparin flush)." Hospira Inc
More about Hep-Lock (heparin flush)
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Further information
Hep-Lock side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.