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Halotestin Side Effects

Generic name: fluoxymesterone

Medically reviewed by Last updated on Jan 8, 2023.

Note: This document contains side effect information about fluoxymesterone. Some dosage forms listed on this page may not apply to the brand name Halotestin.

Applies to fluoxymesterone: oral tablet.

Serious side effects of Halotestin

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of high calcium levels like weakness, confusion, feeling tired, headache, upset stomach and throwing up, constipation, or bone pain.
  • Shortness of breath, a big weight gain, or swelling in the arms or legs.
  • Change in color of skin.
  • Low mood (depression).
  • A burning, numbness, or tingling feeling that is not normal.
  • Upset stomach or throwing up.
  • For males, erections (hard penis) that happen often or that last a long time.
  • For females, a deep voice, facial hair, pimples, or period changes.
  • Very bad and sometimes deadly liver problems have happened with this drug. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.

Other side effects of Halotestin

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Change in sex interest.
  • Anxiety.
  • Headache.
  • Pimples (acne).
  • For males, enlarged breasts.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

For Healthcare Professionals

Applies to fluoxymesterone: compounding powder, oral tablet.


Rare (less than 0.1%): Hepatocellular neoplasms, peliosis hepatis, hepatic coma

Frequency not reported: Cholestatic jaundice, alterations in liver function tests[Ref]


Frequency not reported: Females: Virilization, gonadotropin secretion inhibition, amenorrhea and other menstrual irregularities; Males: Gynecomastia, oligospermia, penile erections of excessive frequency and duration[Ref]


Frequency not reported: Increased serum cholesterol; retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates[Ref]


Frequency not reported: Polycythemia; suppression of clotting factors II, V, VII, and X; bleeding in patients on concomitant anticoagulant therapy[Ref]


Frequency not reported: Hirsutism, male pattern baldness, acne[Ref]


Frequency not reported: Nausea[Ref]

Nervous system

Frequency not reported: Headache, generalized paresthesia[Ref]


Rare (less than 0.1%): Anaphylactoid reactions

Frequency not reported: Hypersensitivity reactions[Ref]


Frequency not reported: Increased or decreased libido, anxiety, depression[Ref]


1. "Product Information. Androxy (fluoxymesterone)." Upsher-Smith Laboratories Inc (2015):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.