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Fomivirsen ophthalmic Side Effects

For the Consumer

Applies to fomivirsen ophthalmic: intraocular solution

Along with its needed effects, fomivirsen ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking fomivirsen ophthalmic:

More common
  • Abnormal vision
  • blurred vision
  • change in how colors look
  • decreased vision or other changes in vision
  • eye pain
  • redness of eye
  • seeing flashes or sparks of light
  • seeing floating spots before eyes
  • sensitivity of eye to light
  • veil or curtain appearing across part of vision
  • watering of eye
Less common
  • Decreased ability to see to the side when looking straight ahead
  • itching, redness, or soreness at place of injection
  • pain on moving the eye
  • soreness of eye
  • swelling of the eye

Some side effects of fomivirsen ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common Less common

For Healthcare Professionals

Applies to fomivirsen ophthalmic: intraocular solution

Ocular

Most adverse effects associated with fomivirsen therapy are limited to the treated eye. However, some of these events (e.g. retinal detachment) will also occur with the natural progression of CMV retinitis and may not necessarily be direct complications of drug administration.

The most frequently observed adverse effect is ocular inflammation, including iritis and vitritis. Inflammatory reactions occur in approximately 25% of patients and are more common during induction dosing. Other frequently reported ocular effects (occurring in 5% to 25% of patients) include abnormal vision, anterior chamber inflammation, blurred vision, cataract, conjunctival hemorrhage, decreased visual acuity, desaturation of color vision, eye pain, floaters, increased intraocular pressure, photophobia, retinal detachment, retinal edema, retinal hemorrhage, and retinal pigment changes. Less commonly (2% to 5%), conjunctival hyperemia, conjunctivitis, corneal edema, decreased peripheral vision, hypotony, keratic precipitates, optic neuritis, photopsia, retinal vascular disease, visual field defect, vitreous hemorrhage, and vitreous opacity have been reported.[Ref]

References

1. Perry CM, Balfour JAB "Fomivirsen." Drugs 57 (1999): 375-80

2. "Product Information. Vitravene (fomivirsen)." Ciba Vision Ophthalmics, Duluth, GA.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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