Fomepizole Side Effects

Medically reviewed by Drugs.com. Last updated on May 10, 2024.

Applies to fomepizole: parenteral injection concentrate for iv infusion.

Side effects include:

Headache, nausea, dizziness, increased drowsiness, bad/metallic taste.

For healthcare professionals

Applies to fomepizole: intravenous solution.

General adverse events

The most common adverse events were headache, nausea, dizziness, increased drowsiness, and bad taste/metallic taste.^[Ref]

Gastrointestinal

• Very common (10% or more): Nausea (11%)
• Common (1% to 10%): Abdominal pain, vomiting, diarrhea, dyspepsia, heartburn^[Ref]

Nervous system

• Very common (10% or more): Headache (14%)
• Common (1% to 10%): Dizziness, increased drowsiness, bad taste/metallic taste, lightheadedness, seizure, agitation, feeling drunk, vertigo, nystagmus, anxiety, "felt strange", decreased environmental awareness, abnormal smell, roar in ear^[Ref]

Other

• Common (1% to 10%): Fever, multiorgan system failure, hangover, speech/visual disturbances^[Ref]

Cardiovascular

• Common (1% to 10%): Sinus bradycardia/bradycardia, phlebosclerosis, tachycardia, phlebitis, shock, hypotension^[Ref]

Hematologic

• Common (1% to 10%): Eosinophilia/hypereosinophilia, lymphangitis, disseminated intravascular coagulation, anemia^[Ref]

Hepatic

• Common (1% to 10%): Transient transaminitis^[Ref]

Local

• Common (1% to 10%): Pain during injection, inflammation at injection site, application site reaction^[Ref]

Genitourinary

• Common (1% to 10%): Anuria^[Ref]

Respiratory

• Common (1% to 10%): Hiccups, pharyngitis^[Ref]

Ocular

• Common (1% to 10%): Transient blurred vision^[Ref]

Dermatologic

• Common (1% to 10%): Facial flush, rash^[Ref]

Musculoskeletal

• Common (1% to 10%): Lumbalgia/backache^[Ref]

Metabolic

• Common (1% to 10%): Decreased appetite

Further information

Fomepizole side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer