Fomepizole Side Effects

Medically reviewed by Drugs.com. Last updated on May 10, 2024.

Applies to fomepizole: parenteral injection concentrate for iv infusion.

Side effects include:

Headache, nausea, dizziness, increased drowsiness, bad/metallic taste.

For healthcare professionals

Applies to fomepizole: intravenous solution.

General adverse events

The most common adverse events were headache, nausea, dizziness, increased drowsiness, and bad taste/metallic taste.^[Ref]

Gastrointestinal

• Very common (10% or more): Nausea (11%)
• Common (1% to 10%): Abdominal pain, vomiting, diarrhea, dyspepsia, heartburn^[Ref]

Nervous system

• Very common (10% or more): Headache (14%)
• Common (1% to 10%): Dizziness, increased drowsiness, bad taste/metallic taste, lightheadedness, seizure, agitation, feeling drunk, vertigo, nystagmus, anxiety, "felt strange", decreased environmental awareness, abnormal smell, roar in ear^[Ref]

Other

• Common (1% to 10%): Fever, multiorgan system failure, hangover, speech/visual disturbances^[Ref]

Cardiovascular

• Common (1% to 10%): Sinus bradycardia/bradycardia, phlebosclerosis, tachycardia, phlebitis, shock, hypotension^[Ref]

Hematologic

• Common (1% to 10%): Eosinophilia/hypereosinophilia, lymphangitis, disseminated intravascular coagulation, anemia^[Ref]

Hepatic

• Common (1% to 10%): Transient transaminitis^[Ref]

Local

• Common (1% to 10%): Pain during injection, inflammation at injection site, application site reaction^[Ref]

Genitourinary

• Common (1% to 10%): Anuria^[Ref]

Respiratory

• Common (1% to 10%): Hiccups, pharyngitis^[Ref]

Ocular

• Common (1% to 10%): Transient blurred vision^[Ref]

Dermatologic

• Common (1% to 10%): Facial flush, rash^[Ref]

Musculoskeletal

• Common (1% to 10%): Lumbalgia/backache^[Ref]

Metabolic

• Common (1% to 10%): Decreased appetite

See also:

Further information

Fomepizole side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer