Eskata Side Effects
Generic name: hydrogen peroxide topical
Medically reviewed by Drugs.com. Last updated on Jun 22, 2025.
Note: This document provides detailed information about Eskata Side Effects associated with hydrogen peroxide topical. Some dosage forms listed on this page may not apply specifically to the brand name Eskata.
Applies to hydrogen peroxide topical: topical application gel/jelly, topical application pad, topical application solution, topical application spray.
Your doctor will check your progress closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to check for unwanted effects.
If your condition does not improve within 3 weeks, or if it becomes worse, check with your doctor.
Using Eskata™ may cause serious eye problems, including blindness. If it accidentally gets into your eyes while you are receiving it, your doctor will tell you to rinse them well with water for 15 to 30 minutes.
The treated area may redden and swelling and scaling may also occur. Your doctor may wait until your skin recovers before continuing with your treatment.
Serious side effects of Eskata
Along with its needed effects, hydrogen peroxide topical (the active ingredient contained in Eskata) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking hydrogen peroxide topical:
More common side effects
- redness, blistering, peeling, or loosening of the skin
- skin burning, itching, pain, rash, stinging, or swelling skin ulcers
Less common side effects
- cracking or scarring of the skin
- thinning, weakness, or wasting away of the skin
Rare side effects
- eyelid swelling
- painful blisters on the trunk of the body
Other side effects of Eskata
Some side effects of hydrogen peroxide topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common side effects
- darkening of the skin
- dryness, peeling, or crusting of the skin
- lightening of normal skin color
- lightening of the treated areas of dark skin
See also:
Frequently asked questions
More about Eskata (hydrogen peroxide topical)
- Check interactions
- Compare alternatives
- Reviews (10)
- Dosage information
- FDA approval history
- Drug class: topical anti-infectives
Patient resources
Other brands
Professional resources
Related treatment guides
Further information
Eskata side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.