Duvoid Side Effects
Generic Name: bethanechol
Note: This document contains side effect information about bethanechol. Some of the dosage forms listed on this page may not apply to the brand name Duvoid.
For the Consumer
Applies to bethanechol: elixir, solution, tablet
Along with its needed effects, bethanechol (the active ingredient contained in Duvoid) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur while taking bethanechol:Rare - more common with the injection
- Shortness of breath, wheezing, or tightness in chest
Some side effects of bethanechol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less common or rare - more common with the injection
- blurred vision or change in near or distance vision
- dizziness or lightheadedness
- feeling faint
- frequent urge to urinate
- increased watering of mouth or sweating
- nausea or vomiting
- redness or flushing of skin or feeling of warmth
- sleeplessness, nervousness, or jitters
- stomach discomfort or pain
For Healthcare Professionals
Applies to bethanechol: compounding powder, oral tablet, subcutaneous solution
Adverse reactions occur more commonly following subcutaneous administration of bethanechol (the active ingredient contained in Duvoid) than with oral administration.
Cholinergic overstimulation with symptoms of circulatory collapse, fall in blood pressure, abdominal cramps, bloody diarrhea, shock, or sudden cardiac arrest has been reported rarely with subcutaneous administration of bethanechol. Atropine sulfate should be available to treat symptoms of toxicity when bethanechol is administered subcutaneously. The adult dose of atropine is 0.6 mg administered subcutaneously every 2 hours, according to patient response.[Ref]
Cardiovascular side effects have included decreased blood pressure with reflex tachycardia and vasomotor response.[Ref]
Nervous system side effects have included headache and seizure. Hypothermia has been reported. An acute dystonic reaction associated with the treatment of gastroesophageal reflux during bethanechol (the active ingredient contained in Duvoid) therapy in an infant has been reported.[Ref]
Gastrointestinal side effects have included abdominal cramps, colicky pain, nausea, vomiting, diarrhea, salivation, and borborygmi.[Ref]
Ocular side effects have included lacrimation and miosis.[Ref]
Renal side effects have included urinary urgency.[Ref]
Respiratory side effects have included aggravation of asthma and bronchial constriction.[Ref]
Dermatologic side effects have included warmth/heat, flushing, and sweating. A case of miliaria crystallina associated with the use of bethanechol (the active ingredient contained in Duvoid) in a diabetic patient with autonomic bladder neuropathy has been reported.[Ref]
1. Caraco Y, Arnon R, Raz I "Bethanechol-induced cholinergic toxicity in diabetic neuropathy [letter." DICP 24 (1990): 327-8
2. "Product Information. Urecholine (bethanechol)." Merck & Co, Inc, West Point, PA.
3. Guerra MF, Ives TJ "Bethanechol and hypothermia [letter]." Ann Intern Med 99 (1983): 279-80
4. Shafrir Y, Levy Y, Beharab A, Nitzam M, Steinherz R "Acute dystonic reaction to bethanechol--a direct acetylcholine receptor agonist." Dev Med Child Neurol 28 (1986): 646-8
5. Berard EJ, Boucand MH, Depassio J, Fyon JP "Effects of bethanechol and adreno-blockers on thermoregulation in spinal cord injury." Paraplegia 27 (1989): 46-50
6. Rochmis PG, Koplon BS "Iatrogenic miliaria crystallina due to bethanechol." Arch Dermatol 95 (1967): 499-500
Some side effects of Duvoid may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
More about Duvoid (bethanechol)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- En Español
- 0 Reviews – Add your own review/rating
- Drug class: miscellaneous genitourinary tract agents
Other brands: Urecholine
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