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Conestat alfa Side Effects

For the Consumer

Applies to conestat alfa: intravenous powder for injection

Get emergency medical help if you have signs of an allergic reaction: rash or hives; chest tightness, wheezing, difficult breathing; blue-colored lips or gums; fast heartbeats; feeling like you might pass out; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • sudden numbness or weakness (especially on one side of the body);

  • sudden severe headache, slurred speech, problems with vision or balance; or

  • pain, swelling, warmth, or redness in one or both legs.

Common side effects may include:

  • headache;

  • diarrhea; or

  • nausea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to conestat alfa: intravenous powder for injection

General

The most common adverse reactions were headache, nausea, and diarrhea.[Ref]

Nervous system

Very common (10% or more): Headache (up to 10%)
Common (1% to 10%): Vertigo, procedural headache
Uncommon (0.1% to 1%): Paresthesia[Ref]

Dermatologic

Common (1% to 10%): Angioedema, erythema marginatum, skin burning sensation
Uncommon (0.1% to 1%): Urticaria
Postmarketing reports: Rash[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, diarrhea
Uncommon (0.1% to 1%): Abdominal discomfort, oral paresthesia
Postmarketing reports: Abdominal pain[Ref]

Respiratory

Common (1% to 10%): Sneezing
Uncommon (0.1% to 1%): Throat irritation[Ref]

Hematologic

Common (1% to 10%): Fibrin D-dimer increased[Ref]

Immunologic

Common (1% to 10%): C-reactive protein increased[Ref]

Musculoskeletal

Common (1% to 10%): Back pain[Ref]

Ocular

Common (1% to 10%): Lipoma

Other

Uncommon (0.1% to 1%): Swelling[Ref]

References

1. "Product Information. Ruconest (conestat alfa)." Valeant Pharmaceuticals, Costa Mesa, CA.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Not all side effects for conestat alfa may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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