Coagulation Factor Ix Side Effects

Medically reviewed by Drugs.com. Last updated on Apr 15, 2025.

Applies to coagulation factor ix: intravenous powder for solution.

Precautions

It is very important that your doctor check you or your child's closely and at regular visits to make sure this medicine is working properly. Blood and urine tests will be needed to check for unwanted effects.

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Tell your doctor or nurse right away if you or your child have a rash, itching skin, difficulty with swallowing, dizziness, a fast heartbeat, lightheadedness or fainting, restlessness, trouble breathing, swelling in your face, hands, tongue, or throat, or chest pain after you receive the medicine.

Check with your doctor right away if you have a cloudy or bloody urine, dizziness, headache, numbness or tingling in the face, arms, or legs, swelling of the face, feet, or lower legs, or vision problems. These may be symptoms of a serious kidney problem called nephrotic syndrome.

This medicine may increase your chance of having blood clotting problems. Tell your doctor right away if you or your child have a sudden or severe headache, problems with vision or speech, chest pain, trouble breathing, or numbness or weakness while you are receiving this medicine.

Call your doctor right away if you or your child start to have bleeding problems, especially if this medicine has worked well for you before.

Serious side effects

Along with its needed effects, coagulation factor ix may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking coagulation factor ix:

Other side effects

Some side effects of coagulation factor ix may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to coagulation factor ix: intravenous kit, intravenous powder for injection.

Hypersensitivity adverse events

• Frequency not reported: Hypersensitivity (including bronchospastic reactions and/or hypotension, anaphylaxis, development of high-titer inhibitors necessitating alternative treatment)^[Ref]

Hematologic

• Common (1% to 10%): Factor IX inhibition^[Ref]

Gastrointestinal

• Common (1% to 10%): Nausea, vomiting^[Ref]

Dermatologic

• Common (1% to 10%): Rash pruritic, hives^[Ref]

Local

• Common (1% to 10%): Injection site discomfort, injection site pain^[Ref]

Nervous system

• Common (1% to 10%): Headache, dysgeusia, lethargy, dizziness, shaking, drowsiness^[Ref]

Respiratory

• Common (1% to 10%): Dry cough, hypoxia, chest tightness, dyspnea^[Ref]

Renal

• Common (1% to 10%): Renal infarct^[Ref]

The renal infarct occurred in a hepatitis C antibody positive patients 12 days after treatment of a bleeding episode; the relation of the infarct to the prior administration of this drug is uncertain.^[Ref]

Ocular

• Common (1% to 10%): Blurred vision^[Ref]

Immunologic

• Common (1% to 10%): Influenza, cellulitis at injection site, phlebitis at injection site^[Ref]

Psychiatric

• Common (1% to 10%): Apathy, depression^[Ref]

Other

• Common (1% to 10%): Hemophilia (lack of efficacy), asthenia, fever, chills^[Ref]

Cardiovascular

• Common (1% to 10%): Flushing^[Ref]

See also:

Further information

Coagulation factor ix side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer