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Cetrotide Side Effects

Generic name: cetrorelix

Medically reviewed by Last updated on Sep 3, 2023.

Note: This document contains side effect information about cetrorelix. Some dosage forms listed on this page may not apply to the brand name Cetrotide.

Applies to cetrorelix: subcutaneous powder for solution.

Serious side effects of Cetrotide

Along with its needed effects, cetrorelix (the active ingredient contained in Cetrotide) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking cetrorelix:

Less common

  • Abdominal or stomach pain
  • continuing or severe nausea, vomiting or diarrhea
  • decreased amount of urine
  • feeling of indigestion
  • moderate to severe bloating
  • pelvic pain, severe
  • rapid weight gain
  • shortness of breath
  • swelling of lower legs

Other side effects of Cetrotide

Some side effects of cetrorelix may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

For Healthcare Professionals

Applies to cetrorelix: subcutaneous powder for injection.


Common (1% to 10%): Mild to moderate ovarian hyperstimulation syndrome (OHSS) (WHO grade I or II)

Uncommon (0.1% to 1%): Severe ovarian hyperstimulation syndrome (WHO grade III)[Ref]


Very common (10% or more): Nausea (12%)[Ref]


The most commonly reported side effects were local injection site reactions such as erythema, swelling, and pruritus that were usually transient in nature and mild in intensity.[Ref]


Uncommon (0.1% to 1%): Systemic allergic/pseudo-allergic reactions including life-threatening anaphylaxis[Ref]


Common (1% to 10%): Redness, erythema, bruising, itching, swelling, pruritus (at the injection site)[Ref]

Nervous system

Common (1% to 10%): Headache[Ref]


1. Product Information. Cetrotide (cetrorelix). Asta Medica. 2001.

2. Cerner Multum, Inc. UK Summary of Product Characteristics.

3. Cerner Multum, Inc. Australian Product Information.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.