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Amlactin XL Side Effects

Generic Name: ammonium lactate topical

Note: This page contains information about the side effects of ammonium lactate topical. Some of the dosage forms included on this document may not apply to the brand name Amlactin XL.

For the Consumer

Applies to ammonium lactate topical: topical cream, topical lotion

Get emergency medical help if you have any of these signs of an allergic reaction while taking ammonium lactate topical (the active ingredient contained in Amlactin XL) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using ammonium lactate topical and call your doctor at once if you have:

  • severe redness or stinging where the medicine was applied.

Common side effects may include:

  • mild dryness or skin irritation after use; or

  • bruising of discoloration of treated skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to ammonium lactate topical: compounding solution, topical cream, topical lotion


Dermatologic side effects have been reported in patients with xerosis including transient stinging (1 in 30 patients), burning (1 in 30 patients), erythema (1 in 50 patients) and peeling (1 in 60 patients). Irritation, eczema, petechiae, dryness, and hyperpigmentation have been reported less frequently.

Due to the more severe initial skin conditions associated with ichthyosis, there was a higher incidence of transient stinging, burning and erythema (each occurring in 1 in 10 patients).[Ref]


1. "Product Information. Laclotion (ammonium lactate topical)." Paddock Laboratories Inc, Minneapolis, MN.

2. "Product Information. Lac-Hydrin (ammonium lactate topical)." Bristol-Myers Squibb, Princeton, NJ.

Not all side effects for Amlactin XL may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

More about Amlactin XL (ammonium lactate topical)

Consumer resources

Other brands: Lac-Hydrin, Laclotion, Geri-Hydrolac, Kerasal AL

Professional resources

Other Formulations

Related treatment guides

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