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Adrenalin Chloride Side Effects

Generic name: epinephrine

Medically reviewed by Drugs.com. Last updated on Mar 2, 2024.

Note: This document provides detailed information about Adrenalin Chloride Side Effects associated with epinephrine. Some dosage forms listed on this page may not apply specifically to the brand name Adrenalin Chloride.

Applies to epinephrine: injection solution.

Other dosage forms:

Serious side effects of Adrenalin Chloride

Along with its needed effects, epinephrine (the active ingredient contained in Adrenalin Chloride) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking epinephrine:

Incidence not known

  • abnormal or decreased touch sensation
  • anxiety
  • arm, back, or jaw pain
  • bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • blurred vision
  • chest pain, tightness, heaviness, or discomfort
  • cold, pale, or bluish color of the skin of the fingers or toes
  • confusion
  • difficulty in speaking
  • dizziness
  • double vision
  • fainting
  • fast, slow, irregular, pounding, or racing heartbeat or pulse
  • headache
  • inability to move the arms, legs, or facial muscles
  • inability to speak
  • nausea
  • numbness, tingling, or pain in the fingers
  • paleness of the skin
  • pounding in the ears
  • restlessness
  • shakiness in the legs, arms, hands, or feet
  • slow speech
  • sweating
  • trembling or shaking of the hands or feet
  • trouble breathing
  • unusual tiredness or weakness
  • vomiting

Get emergency help immediately if any of the following symptoms of overdose occur while taking epinephrine:

Symptoms of overdose

For healthcare professionals

Applies to epinephrine: compounding powder, inhalation aerosol, inhalation solution, injectable kit, injectable solution, intravenous solution, nasal spray, subcutaneous suspension.

General

Due to the lack of randomized, controlled clinical trials for the treatment of anaphylaxis, the true incidence of adverse reactions associated with the systemic use of this drug is difficult to determine. The most commonly reported adverse reactions include anxiety, apprehensiveness, restlessness, tremor, weakness, dizziness, sweating, palpitations, pallor, nausea and vomiting, headache, and/or respiratory difficulties.[Ref]

Cardiovascular

Nervous system

Psychiatric

Local

Dermatologic

Metabolic

Respiratory

Renal

Hypersensitivity

Hypersensitivity side effects have been extremely unusual. Contact dermatitis has been associated with ocularly applied epinephrine (the active ingredient contained in Adrenalin Chloride) These reactions have typically presented with lid edema and a thick yellow discharge.

Gastrointestinal

Genitourinary

Hematologic

Musculoskeletal

Other

Ocular

Endocrine

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

2. Cerner Multum, Inc. "Australian Product Information."

3. (2016) "Product Information. Adrenaclick Two-Pack (epinephrine)." Amedra Pharmaceuticals LLC

4. (2016) "Product Information. Auvi-Q (epinephrine)." sanofi-aventis

5. (2016) "Product Information. EpiPen (epinephrine)." Dey Laboratories

6. (2016) "Product Information. Adrenalin (epinephrine)." A-S Medication Solutions

7. (2016) "Product Information. Epinephrine (epinephrine)." Physicians Total Care

Frequently asked questions

Further information

Adrenalin Chloride side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.