Concurrent Hypertension + Type 2 Diabetes Predict High Mortality Risk
WEDNESDAY, June 4, 2025 -- Adults with concurrent hypertension and type 2 diabetes (T2D) have high mortality risk compared with those who have neither condition or only one, according to a study published online May 28 in Diabetes Care.
Ye Yuan, from Columbia University Irving Medical Center in New York City, and colleagues examined associations of concurrent hypertension and T2D with mortality in a study population of 48,727 adults from the 1999 to 2018 National Health and Nutrition Examination Surveys.
The researchers found that between 1999 and 2018, the burden of concurrent hypertension and T2D doubled from 6 to 12 percent. Overall, 50.5, 38.4, 2.4, and 8.7 percent of participants did not have T2D or hypertension, had hypertension only, had T2D only, and had both, respectively. There were 7,734 deaths during a 9.2-year median follow-up. Higher all-cause and cardiovascular mortality were predicted in association with concurrent hypertension and T2D versus no hypertension or T2D (hazard ratios, 2.46 and 2.97, respectively); stronger associations were seen for women versus men. Concurrent hypertension and T2D predicted up to a 66 percent higher all-cause mortality risk and more than twofold higher cardiovascular mortality risk compared with having hypertension or T2D only; associations varied by sex and race and ethnicity. Compared with having neither or either condition, concurrent prediabetes and elevated blood pressure predicted up to 19 percent higher mortality risk.
"Given the aging U.S. population and the projected rise in chronic disease, our findings underscore the urgent need for innovative public health interventions and policies that address multiple cardiometabolic conditions simultaneously and prioritize chronic disease prevention and the extension of health span meaning the number of years of life lived healthy," senior study author Nour Makarem, Ph.D., from the Columbia University Mailman School of Public Health in New York City, said in a statement.
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Read this next
Hepatitis B Virus Immunity Linked to Reduced Risk for Diabetes
THURSDAY, Sept. 11, 2025 -- Hepatitis B virus (HBV) immunity in individuals without HBV infection is associated with a reduced risk for diabetes, according to a study published...
Online Stock Photos of BP Measurement Rarely Align With Guidelines
TUESDAY, Sept. 9, 2025 -- Few online stock photo images of blood pressure (BP) measurement align with clinical guidelines, according to a study published online Sept. 8 in...
Baxdrostat Reduces Seated Systolic BP in Uncontrolled, Resistant Hypertension
MONDAY, Sept. 8, 2025 -- The addition of baxdrostat, an aldosterone synthase inhibitor, to background therapy yields a significant reduction in seated systolic blood pressure...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.