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Visine Advanced Relief

Generic name: povidone and tetrahydrozoline ophthalmicPOE-vi-done-and-TET-ra-hye-DROZ-oh-leen-off-THAL-mik ]
Drug class: Ophthalmic antihistamines and decongestants

Medically reviewed by on Jan 12, 2024. Written by Cerner Multum.

What is Visine Advanced Relief?

Visine Advanced Relief (for the eyes) is used to relieve eye redness or dryness caused by minor eye irritations, and to protect the eyes from further irritation.

Visine Advanced Relief may also be used for purposes not listed in this medication guide.

Visine Advanced Relief side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Visine Advanced Relief may cause serious side effects. Stop using Visine Advanced Relief and call your doctor at once if you have:

Common side effects of Visine Advanced Relief may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Ask a doctor or pharmacist if this medicine is safe to use if you have ever had glaucoma.

Before taking this medicine

Ask a doctor or pharmacist if Visine Advanced Relief is safe to use if you have ever had glaucoma.

Do not give this medicine to a child younger than 6 years old without medical advice.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

How should I use Visine Advanced Relief?

Use exactly as directed on the label, or as prescribed by your doctor.

Do not use while wearing soft contact lenses. A preservative in this medicine could permanently stain the lenses. Use the medicine at least 15 minutes before inserting your contact lenses.

Wash your hands before using eye medication.

To apply the eye drops: Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye and squeeze a drop into this pocket. Close your eyes for 1 or 2 minutes.

Use only the number of drops recommended on the medicine label.

Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Do not use the medicine if it has changed colors or looks cloudy.

Store this medicine in an upright position at room temperature. Do not freeze.

What happens if I miss a dose?

Since Visine Advanced Relief is used when needed, you may not be on a dosing schedule. Avoid using Visine Advanced Relief more than 4 times in one day. Do not use two doses at one time.

What happens if I overdose?

An overdose of povidone and tetrahydrozoline ophthalmic is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using Visine Advanced Relief?

Do not use other eye medications unless your doctor tells you to.

What other drugs will affect Visine Advanced Relief?

Medicine used in the eyes is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

More about Visine Advanced Relief (povidone / tetrahydrozoline ophthalmic)

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Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.