Skip to Content
Here’s what to ask a doctor about hereditary angioedema


Generic Name: salicylic acid and sodium thiosulfate topical (SAL i SIL ik AS id and SOE dee um THYE oh SUL fate)
Brand Name: Exoderm, Versiclear

What is Versiclear?

Sodium thiosulfate is an antifungal medicine that fights infections caused by fungus.

Salicylic acid helps your skin absorb the sodium thiosulfate.

Versiclear (for the skin) is a combination medicine used to treat a skin infection called tinea versicolor, that appears as white patches on the skin.

Versiclear may also be used for purposes not listed in this medication guide.

Important Information

You should not use Versiclear if you are allergic to sulfa drugs.

Before taking this medicine

You should not use this medicine if you are allergic to salicylic acid, sodium thiosulfate, or sulfa drugs.

It is not known whether Versiclear will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether Versiclear passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I use Versiclear?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Wash your hands before and after applying this medicine, unless you are using it to treat a hand condition.

Before you apply this medicine, wash and thoroughly dry the infected skin.

Shake the lotion well just before each use.

Apply this medication only to the infected skin area. Try not to get any medicine on the healthy skin around the treated area.

Do not cover the treated skin area unless your doctor tells you to.

Rinse with water if this medicine gets in your eyes.

Use Versiclear regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

An overdose of Versiclear is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using Versiclear?

Do not take by mouth. This medicine is for use only on the skin. Do not use this medicine on open wounds or on scraped, irritated, or damaged skin. If this medicine gets in your eyes, nose, mouth, rectum, or vagina, rinse with water.

Avoid using other medications on the areas you treat with Versiclear unless your doctor tells you to.

Versiclear side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Versiclear?

It is not likely that other drugs you take orally or inject will have an effect on topically applied salicylic acid and sodium thiosulfate. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

More about Versiclear (salicylic acid / sodium thiosulfate topical)

Consumer resources

Other brands: Exoderm

Related treatment guides

Where can I get more information?

  • Your pharmacist can provide more information about Versiclear.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 2.01.

Date modified: March 06, 2018
Last reviewed: July 30, 2014