Generic Name: cilostazol (sye LOE sta zol)
Brand Name: Pletal
What is Pletal?
Pletal is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). This medicine dilates arteries that supply blood to your legs. This medicine also improves circulation by keeping platelets in the blood from sticking together and clotting.
Pletal is used to treat the symptoms of intermittent claudication. This condition causes reduced blood flow to the legs, leading to pain while walking. This medicine improves your ability to walk longer distances without pain.
Pletal may also be used for purposes not listed in this medication guide.
Do not take Pletal if you have congestive heart failure.
Before taking this medicine
Do not take Pletal if you have congestive heart failure. This medicine can make this condition worse.
To make sure Pletal is safe for you, tell your doctor if you have:
liver or kidney disease;
heart disease; or
if you smoke.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether Pletal passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
How should I take Pletal?
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Pletal is usually taken twice a day on an empty stomach, at least 30 minutes before or 2 hours after breakfast or dinner.
Take the medicine at the same time each day.
It may take up to 12 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Pletal?
Grapefruit and grapefruit juice may interact with Pletal and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.
Pletal side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
chest pain, pounding heartbeats or fluttering in your chest;
a light-headed feeling, like you might pass out;
fever, chills, body aches, flu symptoms;
bloody urine, painful urination;
shortness of breath, even with mild exertion; or
swelling of your ankles or feet.
Common side effects may include:
diarrhea, abnormal bowel movements;
upset stomach; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Pletal?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Many drugs can interact with Pletal. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all your current medicines and any medicine you start or stop using.
More about Pletal (cilostazol)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Compare Alternatives
- Support Group
- En Español
- 3 Reviews – Add your own review/rating
- Drug class: miscellaneous cardiovascular agents
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about Pletal.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 5.01.
Date modified: January 03, 2018
Last reviewed: July 28, 2017