Skip to Content

Omniscan Prefill Plus

Generic Name: gadodiamide (GAD oh DYE a mide)
Brand Name: Omniscan, Omniscan Prefill Plus

Medically reviewed: January 2, 2018

What is Omniscan Prefill Plus?

Omniscan Prefill Plus is a contrast agent that produces magnetic effects. It is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI.

Omniscan Prefill Plus is used to help diagnose certain disorders of the brain and spine (central nervous system), or the stomach and chest areas.

Omniscan Prefill Plus may also be used for purposes not listed in this medication guide.

Important Information

Omniscan Prefill Plus can cause a life-threatening condition in people with advanced kidney disease. Before receiving this medicine, tell your doctor if you have kidney disease or if you are on dialysis. You may not be able to receive this medicine. Also tell your doctor if you have recently received any contrast agents similar to this medicine.

Before taking this medicine

Omniscan Prefill Plus can cause a life-threatening condition in people with advanced kidney disease. You should not receive this medication if you have kidney disease or if you are on dialysis.

Omniscan Prefill Plus can stay in your body for months or years after you receive this medicine. It is not known whether this could cause any health problems in people whose kidneys work properly. Tell your doctor if you have had repeated scans with a contrast agent, and provide the date of your last scan.

You should not receive Omniscan Prefill Plus if you are allergic to it.

To make sure Omniscan Prefill Plus is safe for you, tell your doctor if you have ever had:

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether Omniscan Prefill Plus passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

How is gadodiamide given?

Omniscan Prefill Plus is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting during your MRI.

Your doctor or other healthcare provider may want to watch you for a short time after your test is over. This is to make sure you do not have any unwanted side effects or delayed reactions.

Omniscan Prefill Plus can cause unusual results with certain medical for 12 to 24 hours after your MRI. Tell any doctor who treats you that you have received this medicine.

What happens if I miss a dose?

Since Omniscan Prefill Plus is used only during your MRI, you will not be on a dosing schedule.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after receiving Omniscan Prefill Plus?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Omniscan Prefill Plus side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects of Omniscan Prefill Plus may occur up to several days after injection.

Omniscan Prefill Plus can cause a life-threatening condition in people with advanced kidney disease. Call your doctor right away if you have any symptoms of this condition, such as:

  • burning, itching, swelling, scaling, and tightening or hardening of your skin;

  • muscle weakness;

  • joint stiffness in your arms, hands, legs, or feet;

  • deep bone pain in your ribs or your hips;

  • trouble moving; or

  • skin redness or discoloration.

Also call your doctor at once if you have:

  • kidney problems--little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath;

  • shortness of breath (even with mild exertion); or

  • chest pain or pressure, pain spreading to your jaw or shoulder.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Omniscan Prefill Plus?

Other drugs may interact with gadodiamide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide