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Generic name: potassium bicarbonatepoe-TAS-ee-um-bye-KAR-bo-nate ]
Brand names: Effer-K, Klor-Con/EF
Drug class: Minerals and electrolytes

Medically reviewed by on Jan 24, 2023. Written by Cerner Multum.

What is Klor-Con/EF?

Potassium is a mineral that is found naturally in foods and is necessary for the normal function of your heart, muscles, and nerves.

Klor-Con/EF is used to treat or prevent low potassium (hypokalemia).

Klor-Con/EF may also be used for purposes not listed in this medication guide.

Klor-Con/EF side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using Klor-Con/EF and call your doctor at once if you have:

  • confusion;

  • fast or irregular heartbeats;

  • a light-headed feeling, like you might pass out;

  • weakness or a heavy feeling in your legs;

  • numbness or tingling in your hands or feet;

  • unusual tiredness;

  • trouble breathing;

  • black, bloody, or tarry stools;

  • severe stomach pain or cramping; or

  • high potassium--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, or loss of movement.

Common side effects of Klor-Con/EF may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


You should not use Klor-Con/EF if you also take a potassium-sparing diuretic such as amiloride, eplerenone, spironolactone, or triamterene.

Before taking this medicine

You should not use Klor-Con/EF if:

  • you have high levels of potassium in your blood; or

  • you also take a potassium-sparing diuretic such as amiloride, eplerenone, spironolactone, or triamterene.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

  • heart problems, irregular heartbeats;

  • diabetes;

  • a severe burn injury;

  • an ulcer or other problems with your stomach or intestines;

  • Addison's disease (an adrenal gland disorder);

  • an allergic reaction to a product that contains potassium;

  • kidney disease; or

  • if you are dehydrated.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Do not give this medicine to a child without medical advice.

How should I take Klor-Con/EF?

Use exactly as directed on the label, or as prescribed by your doctor.

Drop the effervescent tablet into a glass with at least 4 ounces of water. Allow the tablet to dissolve completely. Drink the liquid slowly, over 5 to 10 minutes.

Take your doses at regular intervals to keep a steady amount of potassium in your body at all times.

Take Klor-Con/EF with food or after a meal.

You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if Klor-Con/EF is effective.

You should not stop using Klor-Con/EF without first asking your doctor.

Store this medicine in the original packaging at room temperature away from moisture and heat. Keep each tablet in the foil pouch until you are ready to use the medicine.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Klor-Con/EF?

Avoid using other potassium supplements, salt substitutes, or low-sodium foods unless your doctor has told you to.

What other drugs will affect Klor-Con/EF?

Ask a doctor or pharmacist before using Klor-Con/EF with any other medications, especially:

This list is not complete. Other drugs may affect Klor-Con/EF, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

More about Klor-Con/EF (potassium bicarbonate)

Patient resources

Other brands

Effer-K, Quick-K

Professional resources

Other formulations

Related treatment guides

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.