When is the best time of day to take Wegovy?
Wegovy (semaglutide) can be injected at any time of the day, but you should only inject it once a week. Choose a day of the week that works best for you to stay consistent with your Wegovy injections.
What is Wegovy Used For?
Wegovy contains the active ingredient semaglutide, and it is used together with diet and exercise for weight loss. It is FDA approved for certain people 12 years and older who have been identified as overweight and have a weight-related condition, or those who have been identified as obese.
Wegovy is also FDA approved to lower the risk of major cardiovascular events, such as heart attack and stroke, in adults with heart disease who are overweight or obese. Most recently, it was approved in adults with metabolic-associated steatohepatitis (MASH), also known as nonalcoholic steatohepatitis.
Should I take Wegovy in the Morning or at Night?
It does not matter if you inject Wegovy in the morning or at night. There is not a specific time to inject Wegovy that would make it work better or help you lose weight faster. Choose a time that you will remember to take your injection on the same day every week. It is important to stay consistent with your injections so the amount of medication in your body remains stable.
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Should Wegovy Be Taken With Food?
Unlike many oral medications, Wegovy does not need to be taken with food. Clinical guidelines confirm it can be administered with or without regard to meals, and the medication’s absorption or effectiveness is not affected by eating.
What if I Miss a Dose or Need to Change Injection Days?
Sometimes it may not be possible to take Wegovy on the exact same day each week. According to the manufacturer’s guidance:
- If a dose is missed and the next scheduled dose is more than 2 days (48 hours) away, take the missed dose as soon as possible.
- If less than 2 days until the next dose, skip the missed dose and take the next one at the regularly scheduled time.
- Never take two doses within 48 hours, and do not double up to “catch up.”
This is not all the information you need to know about Wegovy (semaglutide) for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.
References
- U.S. Food and Drug Administration (FDA). (2025, August 15). FDA approves treatment for serious liver disease known as 'MASH'. Retrieved from https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-treatment-serious-liver-disease-known-mash
- Wegovy [package insert]. Updated November 2024. Novo Nordisk. Accessed 01/06/2025 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ee06186f-2aa3-4990-a760-757579d8f77b
Read next
How long until I'll lose weight with Wegovy?
Weight loss may begin within the first 4 weeks of treatment with Wegovy, but the full effects of Wegovy may not be seen for several months or longer. In studies, after 68 weeks, 83% of people taking Wegovy lost 5% or more of their weight compared to 31% of people taking a placebo.
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Which GLP-1 drug is best for weight loss?
The most effective GLP-1 drug for weight loss currently (as of mid-2025) is tirzepatide, marketed under the names Zepbound (for weight loss) and Mounjaro (for diabetes).
Continue reading
Do Ozempic, Wegovy, Mounjaro & Zepbound cause hair loss?
There’s no evidence that hair loss is a direct side effect of Ozempic, Wegovy, Mounjaro or Zepbound. Hair loss is more likely due to the stress of rapid weight loss on your body, which can lead to temporary shedding of hair over several months, a condition known as telogen effluvium.
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Drug information
- Wegovy Information for Consumers
- Wegovy prescribing info & package insert (for Health Professionals)
- Side Effects of Wegovy (detailed)
- Wegovy user reviews (532)
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