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How long does a dose of Varubi last?

Medically reviewed by Last updated on June 29, 2020.

Official Answer


Once you take Varubi, it has a long action in your body with just one dose for up to 5 days. Do not take Varubi more than once every 14 days.

Varubi (generic name: rolapitant) is a substance P/neurokinin 1 (NK1) receptor antagonist used in combination with other medicines to help prevent delayed nausea and vomiting associated with cancer treatment.

Nausea and vomiting that occurs from 1 to 5 days after the start of chemotherapy is referred to as delayed nausea and vomiting, and it can result in serious health complications.

On Day 1 of chemotherapy, take 2 Varubi tablets (180 mg) by mouth about 1 to 2 hours before you receive your anti-cancer medicine (chemotherapy).

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