Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- Cytoxan (cyclophosphamide)
- Ezide (hydrochlorothiazide)
Interactions between your drugs
cycloPHOSphamide hydroCHLOROthiazide
Applies to: Cytoxan (cyclophosphamide), Ezide (hydrochlorothiazide)
Before taking cycloPHOSphamide, tell your doctor if you also use hydroCHLOROthiazide. You may need dose adjustments or special tests in order to safely take both medications together. Your blood work may need to be monitored more frequently or using a different blood pressure medicine may be necessary. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using your medications without first talking to your doctor.
Drug and food interactions
hydroCHLOROthiazide food
Applies to: Ezide (hydrochlorothiazide)
HydroCHLOROthiazide and ethanol (alcohol) may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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