Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- carbamazepine
- Tolsura (itraconazole)
Interactions between your drugs
carBAMazepine itraconazole
Applies to: carbamazepine, Tolsura (itraconazole)
Using itraconazole together with carBAMazepine can alter the blood levels of both medications. Specifically, itraconazole levels may decrease substantially, which may make the medication less effective in treating your fungal infection. At the same time, carBAMazepine levels may increase, and you may experience more frequent and/or severe side effects such as headache, nausea, dizziness, tremor, visual disturbances, weakness, and poor muscle coordination. Talk to you doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
carBAMazepine food
Applies to: carbamazepine
You should preferably avoid the regular consumption of grapefruits and grapefruit juice while taking carBAMazepine. This can cause carBAMazepine levels to increase. You should report signs of carBAMazepine side effects such as nausea, visual disturbances, dizziness, or muscle weakness to your doctor. You should avoid or limit the use of alcohol while being treated with carBAMazepine. Alcohol can increase the nervous system side effects of carBAMazepine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Talk to your doctor or pharmacist if you have any questions or concerns.
itraconazole food
Applies to: Tolsura (itraconazole)
Food increases the absorption of itraconazole capsules but decreases the absorption of itraconazole oral solution. Capsules should be taken immediately after a full meal and the solution be taken on an empty stomach to ensure best results.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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