Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- obecabtagene autoleucel
- Trizivir (abacavir / lamivudine / zidovudine)
Interactions between your drugs
zidovudine obecabtagene autoleucel
Applies to: Trizivir (abacavir / lamivudine / zidovudine), obecabtagene autoleucel
Consumer information for this interaction is not currently available.
MONITOR: Coadministration of zidovudine with other bone marrow depressive or cytotoxic agents may increase the risk and/or severity of zidovudine hematologic toxicity. Zidovudine has been associated with hematologic toxicities such as: neutropenia, granulocytopenia and severe anemia that required blood transfusions particularly in patients with advanced HIV disease.
MANAGEMENT: Hematological parameters should be closely monitored. Some authorities recommend dosages of one or both agents may be adjusted if necessary.
Drug and food interactions
zidovudine food
Applies to: Trizivir (abacavir / lamivudine / zidovudine)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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