Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- Tukysa (tucatinib)
- zafirlukast
Interactions between your drugs
zafirlukast tucatinib
Applies to: zafirlukast, Tukysa (tucatinib)
Zafirlukast may increase the blood levels of tucatinib. This may increase the risk of serious side effects such as liver injury, diarrhea, nausea, vomiting, abdominal pain, and seizures. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
zafirlukast food
Applies to: zafirlukast
Zafirlukast should be taken on an empty stomach 1 hour before or 2 hours after a meal unless otherwise directed by your doctor. You may experience reduced absorption of zafirlukast in the presence of food. This will make it easier for your body to absorb the medication.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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