Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- DurAct (bromfenac)
- Raptiva (efalizumab)
Interactions between your drugs
No drug ⬌ drug interactions were found between the drugs in your list. However, this does not necessarily mean no drug interactions exist. Always consult your healthcare provider.
Drug and food interactions
bromfenac food
Applies to: DurAct (bromfenac)
ADJUST DOSE: In-vivo studies have demonstrated that the absorption of bromfenac is greatly reduced if the drug is taken within three and one-half hours following a high fat meal. The concomitant administration of a high fat meal has led to a 75% reduction in peak plasma concentrations and a 60% reduction in total area under the curve. The mechanism has not been described.
MANAGEMENT: An increased dosage of bromfenac (from 25 to 50 mg) may be needed if a high fat meal is consumed. The clinician may want to warn the patient about subtherapeutic analgesic effects if high fat meals are regularly consumed.
References (1)
- "Product Information. DurAct (bromfenac)." Wyeth-Ayerst Laboratories
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Report options
- Switch to consumer interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
A-G Profen
A-G Profen is used for aseptic necrosis, back pain, chronic myofascial pain, costochondritis ...
Addaprin
Addaprin is used for aseptic necrosis, back pain, chronic myofascial pain, costochondritis, diffuse ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Advil
Advil (ibuprofen) reduces fever, pain and inflammation caused by headaches, toothaches, arthritis ...
Advil Children's
Advil Children's is used for fever, headache, juvenile rheumatoid arthritis, muscle pain, pain ...
Advil Migraine
Advil Migraine is used for headache, juvenile rheumatoid arthritis, pain
Aflaxen
Aflaxen is used for ankylosing spondylitis, aseptic necrosis, back pain, bursitis, chronic ...
Aleve
Aleve is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. Learn ...
Aleve Back and Muscle Pain
Aleve Back and Muscle Pain is used for back pain, muscle pain
Anaprox-DS
Anaprox-DS is used for ankylosing spondylitis, aseptic necrosis, back pain, bursitis, chronic ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.