Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- Bactroban Nasal (mupirocin topical)
- Guaifen PE (guaifenesin / phenylephrine)
Interactions between your drugs
No drug ⬌ drug interactions were found between the drugs in your list. However, this does not necessarily mean no drug interactions exist. Always consult your healthcare provider.
Drug and food/lifestyle interactions
phenylephrine food/lifestyle
Applies to: Guaifen PE (guaifenesin / phenylephrine)
MONITOR: Coadministration of two or more sympathomimetic agents may increase the risk of adverse effects such as nervousness, irritability, and increased heart rate. Central nervous system (CNS) stimulants, particularly amphetamines, can potentiate the adrenergic response to vasopressors and other sympathomimetic agents. Additive increases in blood pressure and heart rate may occur due to enhanced peripheral sympathetic activity.
MANAGEMENT: Caution is advised if two or more sympathomimetic agents are coadministered. Pulse and blood pressure should be closely monitored.
References (7)
- Rosenblatt JE, Lake CR, van Kammen DP, Ziegler MG, Bunney WE Jr (1979) "Interactions of amphetamine, pimozide, and lithium on plasma norepineophrine and dopamine-beta-hydroxylase in schizophrenic patients." Psychiatry Res, 1, p. 45-52
- Cavanaugh JH, Griffith JD, Oates JA (1970) "Effect of amphetamine on the pressor response to tyramine: formation of p-hydroxynorephedrine from amphetamine in man." Clin Pharmacol Ther, 11, p. 656
- (2001) "Product Information. Adderall (amphetamine-dextroamphetamine)." Shire Richwood Pharmaceutical Company Inc
- (2001) "Product Information. Tenuate (diethylpropion)." Aventis Pharmaceuticals
- (2001) "Product Information. Sanorex (mazindol)." Novartis Pharmaceuticals
- (2001) "Product Information. Focalin (dexmethylphenidate)." Mikart Inc
- (2002) "Product Information. Strattera (atomoxetine)." Lilly, Eli and Company
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Report options
- Switch to consumer interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Bactroban
Bactroban (mupirocin) is an antibacterial used to treat skin infections such a impetigo. Includes ...
Rifadin
Rifadin is used for bartonellosis, endocarditis, haemophilus influenzae prophylaxis, legionella ...
Botox
Botox is used cosmetically to reduce facial lines and wrinkles and for medical purposes for ...
Centany
Centany is used for impetigo, nasal carriage of staphylococcus aureus, secondary cutaneous ...
Flagyl
Flagyl is used to treat bacterial infections of the vagina, stomach, skin and joints. Learn about ...
Zosyn
Zosyn is used to treat bacterial infections such as urinary tract and skin infections and ...
Cleocin
Cleocin (clindamycin) is used to treat serious bacterial infections. Includes Cleocin side effects ...
Unasyn
Unasyn is used for aspiration pneumonia, bacterial infection, bone infection, deep neck infection ...
Cefoxitin
Cefoxitin is used for aspiration pneumonia, bacterial infection, bone infection, cesarean section ...
Cilastatin/imipenem
Cilastatin/imipenem is used for aspiration pneumonia, bacteremia, bacterial infection, bone ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.