Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- amphotericin b lipid complex
- digitoxin
Interactions between your drugs
digitoxin amphotericin B lipid complex
Applies to: digitoxin, amphotericin b lipid complex
MONITOR: Although amphotericin does not alter the pharmacokinetics of digoxin, it may increase the risk of toxicity. The mechanism is reduction of serum potassium via renal potassium wasting.
MANAGEMENT: The patient's potassium should be replenished, and serum potassium levels should be checked frequently during therapy. Electrocardiographic monitoring may also be indicated.
References (3)
- Miller R, Bates J (1969) "Amphotericin B toxicity." Ann Intern Med, 71, p. 1089-95
- Cushard WG, Kohanim M, Lantis LR (1969) "Blastomycosis of bone." J Bone Joint Surg Am, 51A, p. 704-12
- "Product Information. Abelcet (amphotericin B lipid complex)." Liposome Company Inc, The
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
Diflucan
Diflucan (fluconazole) is used to treat and prevent fungal infections. Includes Diflucan side ...
Nizoral
Nizoral (ketoconazole) is antifungal antibiotic and is used to treat infections caused by fungus ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Cresemba
Cresemba (isavuconazonium sulfate) is an antifungal medication that may be used to treat invasive ...
AmBisome
Ambisome (amphotericin B) is used to treat serious, life-threatening fungal infections, including a ...
Sporanox
Sporanox (itraconazole) is used to treat fungal infections of the lungs, mouth, throat, toenails ...
Noxafil
Noxafil prevents fungal infections in people with weak immune systems resulting from chemotherapy ...
Mycamine
Mycamine (micafungin) is used to treat infections caused by the Candida fungus. Includes Mycamine ...
Vfend
Vfend (voriconazole) is used to treat infections caused by yeast or other types of fungal ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.