Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- paromomycin
- valacyclovir
Interactions between your drugs
paromomycin valACYclovir
Applies to: paromomycin, valacyclovir
MONITOR: The concurrent use of valacyclovir with other nephrotoxic drugs may increase the risk of renal toxicity. Patients who are elderly, debilitated, dehydrated, or who have preexisting renal dysfunction may have a higher risk of developing adverse reactions. Cases of acute renal failure have been reported.
MANAGEMENT: Close clinical and laboratory monitoring of renal function and drug serum concentrations (if clinically appropriate) is recommended.
References (2)
- (2001) "Product Information. Valtrex (valacyclovir)." Glaxo Wellcome
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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