Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- Inversine (mecamylamine)
- midodrine
Interactions between your drugs
mecamylamine midodrine
Applies to: Inversine (mecamylamine), midodrine
MONITOR: Limited data suggest that methyldopa and other sympatholytics may increase or prolong the pressor effect of sympathomimetics. Hypertension may result. Data exist for phenylpropanolamine and norepinephrine.
MANAGEMENT: If these drugs must be coadministered, blood pressure should be closely monitored. Discontinuation of the sympathomimetic may be necessary if hypertension develops.
References (2)
- McLaren EH (1976) "Severe hypertension produced by interaction of phenylpropanolamine with methyldopa and oxprenolol." Br Med J, 2, p. 283-4
- (2001) "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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