Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- Acular (ketorolac ophthalmic)
- Miochol-E (acetylcholine ophthalmic)
Interactions between your drugs
acetylcholine ophthalmic ketorolac ophthalmic
Applies to: Miochol-E (acetylcholine ophthalmic), Acular (ketorolac ophthalmic)
Limited data have shown that preoperative use of ophthalmic nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce the miotic activity of acetylcholine because of opposing effects. No special interventions appear to be necessary.
References (2)
- Holmes JM, Jay WM (1991) "The effect of preoperative flurbiprofen on miosis produced by acetylcholine during cataract surgery." Am J Ophthalmol, 111, p. 735-8
- (2005) "Product Information. Nevanac (nepafenac ophthalmic)." Alcon Laboratories Inc
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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