Drug Interaction Report

Voriconazole may increase the blood levels and effects of itraconazole. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Food increases the absorption of itraconazole capsules but decreases the absorption of itraconazole oral solution. Capsules should be taken immediately after a full meal and the solution be taken on an empty stomach to ensure best results.

You may experience reduced absorption of voriconazole in the presence of food. Take voriconazole on an empty stomach 1 hour before or 2 hours after a meal unless otherwise directed by your doctor. This will make it easier for your body to absorb the medication.

The recommended maximum number of medicines in the 'antifungal agents' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'antifungal agents' category:

• Tolsura (itraconazole)
• voriconazole

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.