Prograf and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with Prograf (tacrolimus).
Tacrolimus Food
Moderate Food Interaction
Tacrolimus should be taken on a consistent schedule before or after you eat at the same times each day. Grapefruit and grapefruit juice may increase the amount of tacrolimus in your body. This can lead to potentially dangerous side effects and should be avoided. If you are already consuming grapefruit products, do not increase or decrease the amount of these products in your diet without first talking to your doctor.
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Tacrolimus High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
tacrolimus - hypertension
The use of tacrolimus has been associated with hypertension. Therapy with tacrolimus should be administered cautiously in patients with elevated blood pressure. Close monitoring of blood pressure is recommended.
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Prograf drug interactions
There are 870 drug interactions with Prograf (tacrolimus).
Prograf disease interactions
There are 7 disease interactions with Prograf (tacrolimus) which include:
- diabetes mellitus
- hepatic dysfunction
- infections
- QT interval prolongation
- renal dysfunction
- hyperkalemia
- hypertension
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- Drug class: calcineurin inhibitors
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
