Hecoria and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with Hecoria (tacrolimus).
Tacrolimus Food
Moderate Food Interaction
ADJUST DOSING INTERVAL: Consumption of food has led to a 27% decrease in the bioavailability of orally administered tacrolimus.
MANAGEMENT: Tacrolimus should be administered at least one hour before or two hours after meals.
GENERALLY AVOID: Grapefruit juice has been reported to increase tacrolimus trough concentrations. Data are limited, but inhibition of the CYP450 enzyme system appears to be involved.
MANAGEMENT: The clinician may want to recommend that the patient avoid ingesting large amounts of grapefruit juice while taking tacrolimus.
References (2)
- (2001) "Product Information. Prograf (tacrolimus)." Fujisawa
- Hooks MA (1994) "Tacrolimus, a new immunosuppressant--a review of the literature." Ann Pharmacother, 28, p. 501-11
Switch to consumer interaction data
Tacrolimus High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
tacrolimus - hypertension
The use of tacrolimus has been associated with hypertension. Therapy with tacrolimus should be administered cautiously in patients with elevated blood pressure. Close monitoring of blood pressure is recommended.
References (1)
- (2001) "Product Information. Prograf (tacrolimus)." Fujisawa
Switch to consumer interaction data
Hecoria drug interactions
There are 872 drug interactions with Hecoria (tacrolimus).
Hecoria disease interactions
There are 7 disease interactions with Hecoria (tacrolimus) which include:
- diabetes mellitus
- hepatic dysfunction
- infections
- QT interval prolongation
- renal dysfunction
- hyperkalemia
- hypertension
Report options
More about Hecoria (tacrolimus)
- Hecoria consumer information
- Check interactions
- Compare alternatives
- Reviews (1)
- Drug images
- Latest FDA alerts (2)
- Side effects
- Dosage information
- During pregnancy
- Drug class: calcineurin inhibitors
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
CellCept
Cellcept (mycophenolate mofetil) is used to prevent rejection of a kidney, liver, or heart ...
Imuran
Imuran is used for atopic dermatitis, autoimmune hepatitis, chronic active hepatitis, chronic ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Prograf
Prograf is used to prevent your body from rejecting a heart, liver, or kidney transplant. Learn ...
Envarsus XR
Envarsus XR is used for organ transplant, rejection prophylaxis
Afinitor
Afinitor prevents the growth of cancer cells and is used to treat advanced kidney cancer. Learn ...
Astagraf XL
Astagraf XL is used for organ transplant, rejection prophylaxis
Everolimus
Everolimus (Afinitor, Afinitor Disperz, Zortress) belongs to a class of drugs called kinase ...
Sirolimus
Sirolimus systemic is used for lymphangioleiomyomatosis, organ transplant, rejection prophylaxis
Cyclophosphamide
Cyclophosphamide systemic is used for acute lymphocytic leukemia, acute nonlymphocytic leukemia ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
