Ropivacaine and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with ropivacaine.
Caffeine ROPivacaine
Minor Drug Interaction
Ropivacaine serum concentrations may increase when given with drugs metabolized by the CYP450 isoenzyme 1A2. The theorized mechanism is via competitive inhibition. Information is only available from in-vitro studies. The clinical significance is unknown. Consider monitoring the patient more closely for prolonged or excessive ropivacaine effects if these agents are coadministered.
References
- "Product Information. Naropin (ropivacaine)." Astra-Zeneca Pharmaceuticals PROD (2001):
Ropivacaine drug interactions
There are 232 drug interactions with ropivacaine.
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.