Methicillin and Alcohol/Food Interactions

methicillin - sodium/potassium

Each gram of parenteral methicillin sodium contains approximately 60 to 71 mg (2.6 to 3.1 mEq) of sodium and is buffered with 50 mg of sodium citrate. The sodium content should be considered in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension, and fluid retention. In addition, hypokalemia has been reported rarely during therapy with the penicillinase-resistant penicillins, which may be particularly important to bear in mind when treating patients with low potassium reserves or fluid and electrolyte imbalance. Clinical monitoring of electrolytes is recommended if these agents are used for prolonged periods.