Maraviroc and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with maraviroc.
Maraviroc Food
Minor Food Interaction
Administration with food may reduce the bioavailability of maraviroc. According to the product labeling, coadministration of a 300 mg dose of maraviroc with a high-fat breakfast reduced maraviroc peak plasma concentration (Cmax) and systemic exposure (AUC) by 33% in healthy volunteers. However, no food restrictions were used in the clinical studies that demonstrated the safety and efficacy of maraviroc. Therefore, maraviroc can be taken with or without food at the recommended dosage.
References (1)
- (2007) "Product Information. Selzentry (maraviroc)." Pfizer U.S. Pharmaceuticals Group
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Maraviroc drug interactions
There are 390 drug interactions with maraviroc.
Maraviroc disease interactions
There are 3 disease interactions with maraviroc which include:
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- During pregnancy
- Drug class: chemokine receptor antagonist
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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