Orlaam (levomethadyl acetate) and Alcohol / Food Interactions
There is 1 alcohol/food/lifestyle interaction with Orlaam (levomethadyl acetate):
levomethadyl acetate ↔ food
Major Food Interaction
Do not consume grapefruit or grapefruit juice during treatment with levomethadyl acetate unless directed otherwise by your doctor. Grapefruit juice may increase the blood levels of levomethadyl acetate. This can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances (for example, magnesium or potassium loss due to severe or prolonged diarrhea or vomiting). You should also avoid alcohol during treatment, as it may add to the central nervous system effects of levomethadyl acetate and increase the risk of serious side effects such as respiratory depression, low blood pressure, fainting, coma, and even death. Do not drive, operate machinery, or perform other hazardous activities until you know how the medication affects you. Talk to your doctor if you have any questions or concerns. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Orlaam (levomethadyl acetate) drug Interactions
There are 973 drug interactions with Orlaam (levomethadyl acetate)
Orlaam (levomethadyl acetate) disease Interactions
There are 15 disease interactions with Orlaam (levomethadyl acetate) which include:
- Impaired Gi Motility
- Infectious Diarrhea
- Liver Disease
- Renal Dysfunction
- Acute Alcohol Intoxication
- Intracranial Pressure
- Respiratory Depression
- Adrenal Insufficiency
- Biliary Spasm
- Seizure Disorders
- Urinary Retention
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
|Major||Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderate||Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minor||Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
Do not stop taking any medications without consulting your healthcare provider.
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