Bromfenac / prednisolone ophthalmic and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with bromfenac / prednisolone ophthalmic which include:
Moderate Food Interaction
Consumer information for this interaction is not currently available.
ADJUST DOSE: In-vivo studies have demonstrated that the absorption of bromfenac is greatly reduced if the drug is taken within three and one-half hours following a high fat meal. The concomitant administration of a high fat meal has led to a 75% reduction in peak plasma concentrations and a 60% reduction in total area under the curve. The mechanism has not been described.
MANAGEMENT: An increased dosage of bromfenac (from 25 to 50 mg) may be needed if a high fat meal is consumed. The clinician may want to warn the patient about subtherapeutic analgesic effects if high fat meals are regularly consumed.
- "Product Information. Duract (bromfenac)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
NSAIDs - hypertension
NSAIDs including topicals can lead to the onset of new hypertension or worsening of preexisting hypertension, either of which can contribute to the increased incidence of cardiovascular events. Blood pressure should be monitored closely during NSAID therapy and throughout the course of therapy.
Bromfenac / prednisolone ophthalmic drug interactions
There are 354 drug interactions with bromfenac / prednisolone ophthalmic
Bromfenac / prednisolone ophthalmic disease interactions
There are 5 disease interactions with bromfenac / prednisolone ophthalmic which include:
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.