Nucynta ER Drug Interactions
Currently displaying 192 drugs known to have a moderate interaction with Nucynta ER (tapentadol).
Moderate interactions with Nucynta ER (tapentadol)
Note: Showing generic names only.
A
- acrivastine
- albuterol
- aldesleukin
- amifampridine
- apomorphine
- apraclonidine ophthalmic
- arformoterol
- atropine
- azatadine
- azelastine nasal
B
- baricitinib
- belladonna
- benztropine
- biperiden
- bitolterol
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromocriptine
- brompheniramine
C
- cannabidiol
- carbamazepine
- carbetapentane
- carbinoxamine
- cenobamate
- cetirizine
- chlophedianol
- chlorcyclizine
- chlorpheniramine
- clemastine
- clidinium
- clonidine
- clopidogrel
- cyclizine
- cyproheptadine
D
- darifenacin
- desmopressin
- deutetrabenazine
- dexbrompheniramine
- dexchlorpheniramine
- dexmedetomidine
- dicyclomine
- difelikefalin
- dimenhydrinate
- diphenhydramine
- dipivefrin ophthalmic
- divalproex sodium
- dobutamine
- dopamine
- doxylamine
- dronabinol
- droperidol
E
- eluxadoline
- entacapone
- ephedrine
- ephedrine nasal
- epinephrine
- epinephrine ophthalmic
- epinephrine topical
- eslicarbazepine
- ethanol
- ethosuximide
- ethotoin
- ezogabine
F
G
H
I
K
L
- lamotrigine
- levalbuterol
- levetiracetam
- levmetamfetamine nasal
- levocetirizine
- levodopa
- lidocaine
- lindane topical
- lofexidine
M
- maprotiline
- mebrofenin
- meclizine
- melatonin
- mepenzolate
- mephentermine
- mephenytoin
- metaproterenol
- metaraminol
- methdilazine
- methohexital
- methotrimeprazine
- methoxamine
- methscopolamine
- methsuximide
- metoclopramide
- metyrosine
- midazolam
- midodrine
- mitotane
N
O
- olodaterol
- olopatadine nasal
- opicapone
- opium
- oxcarbazepine
- oxybutynin
- oxymetazoline nasal
- oxymetazoline ophthalmic
- oxymetazoline topical
- ozanimod
P
- paramethadione
- pegvisomant
- perampanel
- pergolide
- phenacemide
- phenindamine
- phensuximide
- phenylephrine
- phenylephrine nasal
- phenylephrine ophthalmic
- phenylephrine topical
- phenytoin
- pirbuterol
- polyethylene glycol 3350 with electrolytes
- pramipexole
- prasugrel
- prochlorperazine
- procyclidine
- promethazine
- propantheline
- propylhexedrine nasal
- pseudoephedrine
- pyrilamine
R
S
T
- terbutaline
- tetrabenazine
- tetrahydrozoline nasal
- tetrahydrozoline ophthalmic
- thalidomide
- thiethylperazine
- thiopental
- tiagabine
- ticagrelor
- tirzepatide
- tofacitinib
- tolcapone
- tolterodine
- topiramate
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- tripelennamine
- triprolidine
- trospium
U
V
X
Z
Nucynta ER alcohol/food interactions
There is 1 alcohol/food interaction with Nucynta ER (tapentadol).
Nucynta ER disease interactions
There are 14 disease interactions with Nucynta ER (tapentadol) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- biliary tract disease
More about Nucynta ER (tapentadol)
- Nucynta ER consumer information
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- Compare alternatives
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- Reviews (81)
- Drug images
- Latest FDA alerts (1)
- Side effects
- Dosage information
- During pregnancy
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.