Preparation H Cooling Gel Interactions
There are 45 drugs known to interact with Preparation H Cooling Gel (phenylephrine topical), along with 3 disease interactions. Of the total drug interactions, 6 are major, and 39 are moderate.
- View all 45 medications that may interact with Preparation H Cooling Gel
- View Preparation H Cooling Gel disease interactions (3)
Most frequently checked interactions
View interaction reports for Preparation H Cooling Gel (phenylephrine topical) and the medicines listed below.
- acetaminophen
- Allegra (fexofenadine)
- amoxicillin
- azithromycin
- Benadryl (diphenhydramine)
- benzonatate
- calcium / vitamin d
- cetirizine
- Colace (docusate)
- cyclobenzaprine
- Flonase (fluticasone nasal)
- fluticasone nasal
- gabapentin
- guaifenesin
- hydroxyzine
- ibuprofen
- levothyroxine
- loratadine
- melatonin
- meloxicam
- MiraLAX (polyethylene glycol 3350)
- Mucinex (guaifenesin)
- multivitamin
- rosuvastatin
- trazodone
- Tums Extra Strength 750 (calcium carbonate)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- zinc gluconate
Preparation H Cooling Gel disease interactions
There are 3 disease interactions with Preparation H Cooling Gel (phenylephrine topical) which include:
Report options
More about Preparation H Cooling Gel (phenylephrine topical)
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- Reviews (2)
- Side effects
- Drug class: anorectal preparations
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.