Mitotane Drug Interactions
Currently displaying a list of 620 drugs known to interact with mitotane.
- 206 major drug interactions
- 400 moderate drug interactions
- 14 minor drug interactions
Medications known to interact with mitotane
Note: Showing generic names only.
A
- abemaciclib
- abiraterone
- acalabrutinib
- acetylcarbromal
- acoramidis
- acrivastine
- adagrasib
- albendazole
- aldesleukin
- alfentanil
- alpelisib
- alprazolam
- amiodarone
- amisulpride
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amprenavir
- anisindione
- apixaban
- apomorphine
- apremilast
- aprepitant
- aripiprazole
- armodafinil
- asciminib
- asenapine
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- atazanavir
- atogepant
- atorvastatin
- atrasentan
- atropine
- avacopan
- avanafil
- avapritinib
- avatrombopag
- axitinib
- azatadine
- azelastine nasal
B
- baclofen
- bedaquiline
- belladonna
- belumosudil
- benztropine
- bepridil
- berotralstat
- betamethasone
- bexarotene
- biperiden
- black cohosh
- boceprevir
- bortezomib
- bosentan
- bosutinib
- brentuximab
- brexanolone
- brexpiprazole
- brigatinib
- brivaracetam
- bromocriptine
- brompheniramine
- budesonide
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabazitaxel
- cabergoline
- cabozantinib
- calaspargase pegol
- calcifediol
- calcitriol
- cannabidiol
- cannabis
- capivasertib
- capmatinib
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- caspofungin
- cenobamate
- ceritinib
- cerivastatin
- cetirizine
- cevimeline
- chlophedianol
- chloral hydrate
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chloroquine
- chlorotrianisene
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorzoxazone
- cholecalciferol
- citalopram
- clarithromycin
- clemastine
- clindamycin
- clobazam
- clofarabine
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- cobicistat
- cobimetinib
- codeine
- conjugated estrogens
- copanlisib
- crinecerfont
- crizotinib
- cyclizine
- cyclobenzaprine
- cyclosporine
- cyproheptadine
D
- dabrafenib
- daclatasvir
- daclizumab
- dantrolene
- dapsone topical
- daridorexant
- darifenacin
- darolutamide
- darunavir
- dasatinib
- deflazacort
- delavirdine
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexamethasone
- dexbrompheniramine
- dexchlorpheniramine
- dexmedetomidine
- dextromethorphan
- dezocine
- diazepam
- dicumarol
- dicyclomine
- dienestrol topical
- difelikefalin
- dihydroergotamine
- dihydrotachysterol
- diltiazem
- dimenhydrinate
- diphenhydramine
- divalproex sodium
- docetaxel
- dofetilide
- donepezil
- doravirine
- doxazosin
- doxepin
- doxepin topical
- doxercalciferol
- doxorubicin
- doxorubicin liposomal
- doxylamine
- dronabinol
- dronedarone
- droperidol
- drospirenone
- duloxetine
- duvelisib
E
- efavirenz
- elacestrant
- elagolix
- eliglustat
- elvitegravir
- encorafenib
- enfortumab vedotin
- entacapone
- entrectinib
- enzalutamide
- epirubicin
- eplerenone
- eravacycline
- erdafitinib
- ergocalciferol
- ergonovine
- ergotamine
- erlotinib
- erythromycin
- escitalopram
- esketamine
- eslicarbazepine
- estazolam
- esterified estrogens
- estradiol
- estradiol topical
- estrone
- estropipate
- estropipate topical
- eszopiclone
- ethanol
- ethchlorvynol
- ethinyl estradiol
- ethosuximide
- ethotoin
- etonogestrel
- etoposide
- etranacogene dezaparvovec
- etravirine
- everolimus
- exemestane
- ezogabine
F
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fentanyl
- fesoterodine
- fexinidazole
- fidanacogene elaparvovec
- finerenone
- flavoxate
- flibanserin
- fludrocortisone
- fluoxetine
- fluphenazine
- flurazepam
- fluticasone
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fostamatinib
- fostemsavir
- fruquintinib
G
- gabapentin
- gabapentin enacarbil
- ganaxolone
- gefitinib
- gepirone
- gilteritinib
- glasdegib
- guanabenz
- guanfacine
H
- halazepam
- haloperidol
- heroin
- hydrocodone
- hydrocortisone
- hydromorphone
- hydroxychloroquine
- hydroxyprogesterone
- hydroxyzine
- hyoscyamine
I
- ibrexafungerp
- ibrutinib
- idelalisib
- ifosfamide
- iloperidone
- imatinib
- imipramine
- indinavir
- infigratinib
- interferon beta-1a
- interferon beta-1b
- irinotecan
- irinotecan liposomal
- isavuconazonium
- isocarboxazid
- isoniazid
- isradipine
- istradefylline
- itraconazole
- ivabradine
- ivacaftor
- ivosidenib
- ixabepilone
- ixazomib
K
L
- lacosamide
- lamotrigine
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- lenacapavir
- leniolisib
- levamlodipine
- levetiracetam
- levobupivacaine
- levocetirizine
- levodopa
- levoketoconazole
- levomethadyl acetate
- levonorgestrel
- levorphanol
- lidocaine
- linagliptin
- lithium
- lofexidine
- lomitapide
- lonafarnib
- lorazepam
- lorlatinib
- lovastatin
- loxapine
- lumateperone
- lurasidone
- lurbinectedin
M
- macimorelin
- macitentan
- maprotiline
- maraviroc
- maribavir
- mavacamten
- mavorixafor
- meclizine
- medroxyprogesterone
- mefloquine
- megestrol
- melatonin
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methdilazine
- methocarbamol
- methohexital
- methotrexate
- methotrimeprazine
- methsuximide
- methyldopa
- methylergonovine
- methylprednisolone
- methysergide maleate
- metoclopramide
- metyrosine
- mibefradil
- midazolam
- midostaurin
- mifepristone
- mipomersen
- mirabegron
- mirtazapine
- mitapivat
- mobocertinib
- modafinil
- molindone
- momelotinib
- montelukast
- morphine
- morphine liposomal
N
- nabilone
- nalbuphine
- naldemedine
- naloxegol
- naltrexone
- nateglinide
- nefazodone
- nelfinavir
- neratinib
- nevirapine
- nicardipine
- nifedipine
- nilotinib
- nimodipine
- niraparib
- nirogacestat
- nisoldipine
- nitisinone
- norethindrone
- norgestrel
- nortriptyline
O
- olanzapine
- olaparib
- oliceridine
- olopatadine nasal
- olutasidenib
- omaveloxolone
- ondansetron
- opicapone
- opium
- orphenadrine
- osilodrostat
- osimertinib
- ospemifene
- oxazepam
- oxcarbazepine
- oxybutynin
- oxycodone
- oxymorphone
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- paliperidone
- palovarotene
- panobinostat
- paraldehyde
- paramethadione
- paricalcitol
- paroxetine
- pazopanib
- pegaspargase
- peginterferon beta-1a
- pemigatinib
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perphenazine
- pexidartinib
- phenacemide
- phencyclidine
- phenelzine
- phenindamine
- phenobarbital
- phensuximide
- phenytoin
- pimavanserin
- pimozide
- pirtobrutinib
- pitolisant
- polatuzumab vedotin
- pomalidomide
- ponatinib
- pralsetinib
- pramipexole
- praziquantel
- prazosin
- prednisolone
- prednisone
- pregabalin
- pretomanid
- primidone
- prochlorperazine
- procyclidine
- progesterone
- progesterone topical
- promazine
- promethazine
- propiomazine
- propofol
- propoxyphene
- protriptyline
- pyrilamine
Q
R
- ramelteon
- ranolazine
- rasagiline
- red yeast rice
- regorafenib
- relugolix
- remdesivir
- remifentanil
- remimazolam
- repaglinide
- repotrectinib
- revumenib
- ribociclib
- rifabutin
- rifampin
- rilpivirine
- rimegepant
- riociguat
- ripretinib
- risperidone
- ritlecitinib
- ritonavir
- rivaroxaban
- roflumilast
- rolapitant
- romidepsin
- ropeginterferon alfa-2b
- ropinirole
- ropivacaine
- rotigotine
- rucaparib
- rufinamide
- ruxolitinib
- ruxolitinib topical
S
- safinamide
- samarium sm 153 lexidronam
- saquinavir
- saxagliptin
- scopolamine
- secobarbital
- selegiline
- selinexor
- selpercatinib
- selumetinib
- sertraline
- sibutramine
- sildenafil
- silodosin
- simeprevir
- simvastatin
- siponimod
- sirolimus
- sirolimus protein-bound
- solifenacin
- sonidegib
- sorafenib
- sotorasib
- sparsentan
- spironolactone
- st. john's wort
- stiripentol
- sufentanil
- sunitinib
- suvorexant
- suzetrigine
T
- tacrolimus
- tadalafil
- tamoxifen
- tapentadol
- tasimelteon
- tazemetostat
- telaprevir
- telithromycin
- temazepam
- temsirolimus
- teniposide
- tepotinib
- terazosin
- teriflunomide
- tetrabenazine
- thalidomide
- thiethylperazine
- thioguanine
- thiopental
- thioridazine
- thiotepa
- thiothixene
- tiagabine
- ticagrelor
- tinidazole
- tipranavir
- tisotumab vedotin
- tivozanib
- tizanidine
- tofacitinib
- tolcapone
- tolterodine
- tolvaptan
- topiramate
- toremifene
- trabectedin
- tramadol
- tranylcypromine
- trazodone
- tretinoin
- triamcinolone
- triazolam
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- troleandomycin
- tucatinib
U
V
- valbenazine
- valerian
- valoctocogene roxaparvovec
- valproic acid
- vamorolone
- vandetanib
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vigabatrin
- vilazodone
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- voclosporin
- vonoprazan
- vorapaxar
- voriconazole
- vortioxetine
- voxelotor
W
Z
Mitotane alcohol/food interactions
There is 1 alcohol/food interaction with mitotane.
Mitotane disease interactions
There are 5 disease interactions with mitotane which include:
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More about mitotane
- mitotane consumer information
- Check interactions
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: miscellaneous antineoplastics
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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