Drug Interactions between metformin and Methotrexate LPF Sodium
This report displays the potential drug interactions for the following 2 drugs:
- Methotrexate LPF Sodium (methotrexate)
Interactions between your drugs
No interactions were found between metformin and Methotrexate LPF Sodium. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
- Metformin is in the drug class non-sulfonylureas.
- Metformin is used to treat the following conditions:
Methotrexate LPF Sodium
A total of 595 drugs are known to interact with Methotrexate LPF Sodium.
- Methotrexate lpf sodium is in the following drug classes: antimetabolites, antipsoriatics, antirheumatics, other immunosuppressants.
Methotrexate lpf sodium is used to treat the following conditions:
- Acute Lymphoblastic Leukemia
- Acute Lymphocytic Leukemia
- Breast Cancer
- Graft-versus-host disease
- Head and Neck Cancer
- Meningeal Leukemia
- Mycosis Fungoides
- Neoplastic Diseases
- Non-Hodgkin's Lymphoma
- Non-Small Cell Lung Cancer
- Psoriatic Arthritis
- Rheumatoid Arthritis
- Small Cell Lung Cancer
- Solid Tumors
- Systemic Sclerosis
- Trophoblastic Disease
Drug and food interactions
Applies to: metformin
MetFORMIN should be taken with meals, and excessive alcohol intake (either short-term binge drinking or frequent consumption) should be avoided during treatment. Taking metFORMIN with alcohol may increase the risk of a rare but serious and potentially life-threatening condition known as lactic acidosis, which is a buildup of lactic acid in the blood that can occasionally occur during treatment with metformin-containing products. Lactic acidosis is more likely to occur if you have kidney or liver disease, acute or unstable congestive heart failure, or dehydration. You should seek immediate medical attention if you develop potential signs and symptoms of lactic acidosis such as fatigue, weakness, muscle pain, increasing drowsiness, abdominal pain or discomfort, slow or irregular heartbeat, breathing difficulty, chills, and other unusual symptoms. Alcohol may also affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink. You should avoid using alcohol if your diabetes is not well controlled or if you have high triglycerides, neuropathy (nerve damage), or pancreatitis. Moderate alcohol consumption generally does not affect blood glucose levels if your diabetes is under control. However, you should limit your alcohol intake due to the risk of lactic acidosis with metformin. Avoid drinking alcohol on an empty stomach or following exercise, as it may increase the risk of hypoglycemia. Talk to your doctor or pharmacist if you have any questions or concerns about metformin.
Applies to: Methotrexate LPF Sodium (methotrexate)
Caffeine may reduce the effectiveness of methotrexate in the treatment of arthritis. If you are receiving methotrexate for arthritis, you may want to limit your intake of caffeine-containing foods and medications. Check with your doctor or pharmacist if you have concerns or are uncertain what products may contain caffeine.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.