Can you take Linvoseltamab with Risa-Bid?
1 drug interaction and 6 additional warnings found for the following 2 drugs:
- linvoseltamab
- Risa-Bid (lactobacillus acidophilus)
Drug interactions
Moderate drug interactions
Moderate:
lactobacillus acidophilus linvoseltamab
Applies to: Risa-Bid (lactobacillus acidophilus) and linvoseltamab
If you are currently being treated or have recently been treated with linvoseltamab, you should let your doctor know before using lactobacillus acidophilus. Depending on the dose and length of time you have been on linvoseltamab, you may be at risk for developing rare infections from exposure to products containing live bacteria or yeast. Depending on your overall health and medical condition, it may be advisable to avoid using lactobacillus acidophilus until your immune system has recovered from the effects of linvoseltamab. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease interactions
6 potential interactions Applies to: 5 conditions, including Liver Disease, Infection, Immunodeficiency, Neutropenia, and Renal Dysfunction.
Immunodeficiency
Moderate:
linvoseltamab
Linvoseltamab has a moderate potential interaction with Immunodeficiency.
Linvoseltamab can cause serious, life-threatening, or fatal infections. Neutropenia and febrile neutropenia have been reported with use of linvoseltamab. Assess patients for signs and symptoms of preexisting infection before starting therapy. Evaluate immunoglobulin levels and complete blood cell counts at baseline. Monitor for infection during treatment, especially in patients with neutropenia. Administer prophylactic anti-infectives, vaccines, and immunoglobulin according to clinical guidelines.
Moderate:
Risa-Bid
The lactobacillus acidophilus in Risa-Bid has a moderate potential interaction with Immunodeficiency.
Probiotics, especially those containing lactobacillus, should be used with caution in immunosuppressed patients.
Infection
Moderate:
linvoseltamab
Linvoseltamab has a moderate potential interaction with Infection.
Linvoseltamab can cause serious, life-threatening, or fatal infections. Neutropenia and febrile neutropenia have been reported with use of linvoseltamab. Assess patients for signs and symptoms of preexisting infection before starting therapy. Evaluate immunoglobulin levels and complete blood cell counts at baseline. Monitor for infection during treatment, especially in patients with neutropenia. Administer prophylactic anti-infectives, vaccines, and immunoglobulin according to clinical guidelines.
Liver Disease
Moderate:
linvoseltamab
Linvoseltamab has a moderate potential interaction with Liver Disease.
The effect of moderate to severe liver dysfunction (total bilirubin greater than 1.5 times the upper limit of normal with any AST) on the pharmacokinetics of linvoseltamab is unknown. Due to the risk of hepatotoxicity with linvoseltamab, monitor liver enzymes and bilirubin at baseline and during treatment as indicated.
Neutropenia
Moderate:
linvoseltamab
Linvoseltamab has a moderate potential interaction with Neutropenia.
Linvoseltamab can cause serious, life-threatening, or fatal infections. Neutropenia and febrile neutropenia have been reported with use of linvoseltamab. Assess patients for signs and symptoms of preexisting infection before starting therapy. Evaluate immunoglobulin levels and complete blood cell counts at baseline. Monitor for infection during treatment, especially in patients with neutropenia. Administer prophylactic anti-infectives, vaccines, and immunoglobulin according to clinical guidelines.
Renal Dysfunction
Moderate:
linvoseltamab
Linvoseltamab has a moderate potential interaction with Renal Dysfunction.
The effect of severe renal dysfunction/end-stage renal disease (CrCl 29 mL/min or less) on the pharmacokinetics of linvoseltamab is unknown.
Report options
More resources
linvoseltamab
A total of 454 drugs are known to interact with linvoseltamab.
- Linvoseltamab is in the drug class bispecific T-cell engagers (BiTE).
- Linvoseltamab is used to treat Multiple Myeloma.
Risa-Bid
A total of 370 drugs are known to interact with Risa-Bid.
- Risa-bid is in the following drug classes: antidiarrheals, probiotics.
- Risa-bid is used to treat the following conditions:
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.