Drug Interactions between ciprofloxacin and Rimactane
This report displays the potential drug interactions for the following 2 drugs:
- ciprofloxacin
- Rimactane (rifampin)
Interactions between your drugs
No interactions were found between ciprofloxacin and Rimactane. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
ciprofloxacin
A total of 671 drugs are known to interact with ciprofloxacin.
- Ciprofloxacin is in the drug class quinolones and fluoroquinolones.
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Ciprofloxacin is used to treat the following conditions:
- Anthrax
- Anthrax Prophylaxis
- Bacteremia
- Bacterial Infection
- Bladder Infection
- Bone infection
- Bronchiectasis
- Bronchitis
- Chancroid
- Cholera
- Crohn's Disease, Active (off-label)
- Cutaneous Bacillus anthracis
- Diverticulitis
- Epididymitis, Sexually Transmitted
- Febrile Neutropenia
- Gastrointestinal Perforation (off-label)
- Gonococcal Infection, Disseminated
- Gonococcal Infection, Uncomplicated
- Granuloma Inguinale
- Infection Prophylaxis
- Infectious Diarrhea
- Intraabdominal Infection
- Joint Infection
- Kidney Infections
- Meningococcal Disease Prophylaxis
- Mycobacterium avium-intracellulare, Treatment
- Nosocomial Pneumonia
- Peritonitis
- Plague
- Plague Prophylaxis
- Pneumonia
- Pneumonia with Cystic Fibrosis
- Pouchitis
- Prostatitis
- Rabbit Fever
- Salmonella Enteric Fever
- Salmonella Gastroenteritis
- Shigellosis
- Sinusitis
- Skin and Structure Infection
- Skin or Soft Tissue Infection
- Surgical Prophylaxis
- Traveler's Diarrhea
- Tuberculosis, Active
- Typhoid Fever
- Urinary Tract Infection
Rimactane
A total of 721 drugs are known to interact with Rimactane.
- Rimactane is in the drug class rifamycin derivatives.
- Rimactane is used to treat the following conditions:
Drug and food interactions
ciprofloxacin food
Applies to: ciprofloxacin
Do not take ciprofloxacin with dairy products such as milk or yogurt, or with calcium-fortified foods (e.G., cereal, juice). You may eat or drink dairy products or calcium-fortified foods with a regular meal, but do not use them alone when taking ciprofloxacin. They could make the medication less effective. When ciprofloxacin tablets are given with enteral (tube) feedings, ciprofloxacin may not work as well. You could interrupt the feeding for 1 hour before and 2 hours after the ciprofloxacin dose, or your doctor may decide to switch to a different treatment. Ciprofloxacin oral suspension should not be given via nasogastric tubes or feeding tubes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
rifAMPin food
Applies to: Rimactane (rifampin)
Consumer information for this interaction is not currently available.
GENERALLY AVOID: Concurrent use of rifampin in patients who ingest alcohol daily may result in an increased incidence of hepatotoxicity. The increase in hepatotoxicity may be due to an additive risk as both alcohol and rifampin are individually associated with this adverse reaction. However, the exact mechanism has not been established.
ADJUST DOSING INTERVAL: Administration with food may reduce oral rifampin absorption, increasing the risk of therapeutic failure or resistance. In a randomized, four-period crossover phase I study of 14 healthy male and female volunteers, the pharmacokinetics of single dose rifampin 600 mg were evaluated under fasting conditions and with a high-fat meal. Researchers observed that administration of rifampin with a high-fat meal reduced rifampin peak plasma concentration (Cmax) by 36%, nearly doubled the time to reach peak plasma concentration (Tmax) but reduced overall exposure (AUC) by only 6%.
MANAGEMENT: The manufacturer of oral forms of rifampin recommends administration on an empty stomach, 30 minutes before or 2 hours after meals. Patients should be encouraged to avoid alcohol or strictly limit their intake. Patients who use alcohol and rifampin concurrently or have a history of alcohol use disorder may require additional monitoring of their liver function during treatment with rifampin.
References
- "Product Information. Rifampin (rifAMPin)." Akorn Inc (2022):
- "Product Information. Rifampicin (rifampicin)." Mylan Pharmaceuticals Inc (2022):
- "Product Information. Rifadin (rifampicin)." Sanofi (2023):
- "Product Information. Rifadin (rifaMPICin)." Sanofi-Aventis Australia Pty Ltd (2024):
- Peloquin CA, Namdar R, Singleton MD, Nix DE "Pharmacokinetics of rifampin under fasting conditions, with food, and with antacids https://pubmed.ncbi.nlm.nih.gov/9925057/" (2024):
- "Product Information. Rofact (rifampin)." Bausch Health, Canada Inc. (2019):
ciprofloxacin food
Applies to: ciprofloxacin
Ciprofloxacin and multivitamin with minerals should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of ciprofloxacin into the bloodstream and reduce its effectiveness. If possible, it may be best to avoid taking multivitamin with minerals while you are being treated with ciprofloxacin. Otherwise, ciprofloxacin should be taken 2 to 4 hours before or 4 to 6 hours after a multivitamin with minerals dose, ciprofloxacin should be taken at least 2 hours before and not less than 6 hours after Suprep Bowel Prep (magnesium/potassium/sodium sulfates), or ciprofloxacin and multivitamin with minerals should be taken as directed by your healthcare provider. Talk to your healthcare provider if you are unsure whether your medications contain something that could potentially interact or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ciprofloxacin food
Applies to: ciprofloxacin
Using caffeine together with ciprofloxacin may increase the effects of caffeine. Contact your doctor if you experience headache, tremor, restlessness, nervousness, insomnia, and increased blood pressure or heart rate. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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