Skip to main content

Can You Take Cimetidine with PNV 27-Ca/Fe/FA?

This report displays the potential drug interactions for the following 2 drugs:

Edit list (add/remove drugs)

Interactions between your drugs

Minor

cimetidine multivitamin, prenatal

Applies to: cimetidine and PNV 27-Ca/Fe/FA (multivitamin, prenatal)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug and food/lifestyle interactions

Moderate

multivitamin, prenatal food/lifestyle

Applies to: PNV 27-Ca/Fe/FA (multivitamin, prenatal)

Food may reduce the absorption and blood levels of multivitamin, prenatal. In addition, some oral medications can also interfere with multivitamin, prenatal absorption into the bloodstream, which may make the medication less effective in treating your condition. Likewise, multivitamin, prenatal may interfere with the absorption of other orally administered medications. You should take multivitamin, prenatal on an empty stomach at least one hour before or two hours after a meal. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Talk to your doctor or pharmacist if you have questions about how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Minor

cimetidine food/lifestyle

Applies to: cimetidine

Information for this minor interaction is available on the professional version.

Minor

cimetidine food/lifestyle

Applies to: cimetidine

Information for this minor interaction is available on the professional version.

Minor

cimetidine food/lifestyle

Applies to: cimetidine

Information for this minor interaction is available on the professional version.

Disease interactions

Major

cimetidine Gastrointestinal Hemorrhage

Applies to: Gastrointestinal Hemorrhage

Histamine H2 receptor antagonists should not be used in the presence of vomit with blood, or bloody or black stools. These might be serious conditions and the diagnosis needs to be ruled out.

Major

cimetidine Liver Disease

Applies to: Liver Disease

Cimetidine is partially metabolized by the liver, and to a greater extent when administered orally than when given intravenously. Although dosage reductions are generally not necessary, therapy with cimetidine should be administered cautiously in patients with liver disease. Hepatotoxicity has been associated with cimetidine use. In addition, liver disease appears to be a risk factor for cimetidine-related central nervous system toxicity, which may include mental confusion, agitation, psychosis, depression, anxiety, hallucinations, and disorientation. These effects are usually reversible within 3 to 4 days after discontinuation of therapy.

Moderate

cimetidine hemodialysis

Applies to: hemodialysis

Cimetidine is partially removed by hemodialysis and should be administered after dialysis.

Moderate

cimetidine Renal Dysfunction

Applies to: Renal Dysfunction

Cimetidine and its metabolites are primarily eliminated by the kidney. The daily dosage should initially be reduced in patients with moderate to severe renal impairment (CrCl < 50 mL/min). If necessary, the daily dosage may be increased with caution. Renal dysfunction also appears to be a risk factor for cimetidine-related central nervous system toxicity, which may include mental confusion, agitation, psychosis, depression, anxiety, hallucinations, and disorientation. These effects are generally reversible within 3 to 4 days after discontinuation of therapy.

cimetidine

A total of 493 drugs are known to interact with cimetidine.

PNV 27-Ca/Fe/FA

A total of 172 drugs are known to interact with PNV 27-Ca/Fe/FA.


Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.