Acetaminophen / caffeine / chlorpheniramine / phenylpropanolamine Drug Interactions
A total of 514 drugs are known to interact with acetaminophen / caffeine / chlorpheniramine / phenylpropanolamine.
- 62 major drug interactions
- 423 moderate drug interactions
- 29 minor drug interactions
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Medications known to interact with acetaminophen / caffeine / chlorpheniramine / phenylpropanolamine
Note: Showing generic names only.
Include all brand names and combination drug names.
A
- abiraterone
- abobotulinumtoxinA
- acarbose
- acetohexamide
- acetylcarbromal
- acetylcholine ophthalmic
- aclidinium
- acrivastine
- adenosine
- albiglutide
- albuterol
- alfentanil
- alogliptin
- alosetron
- alprazolam
- amantadine
- amifampridine
- amitriptyline
- amobarbital
- amoxapine
- amphetamine
- anagrelide
- anisindione
- apalutamide
- apomorphine
- apraclonidine ophthalmic
- arformoterol
- aripiprazole
- asenapine
- aspirin
- atazanavir
- atomoxetine
- atropine
- azatadine
- azelastine nasal
B
- baclofen
- bedaquiline
- belladonna
- bendamustine
- benzphetamine
- benztropine
- biperiden
- bitolterol
- black cohosh
- brentuximab
- brexpiprazole
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromocriptine
- brompheniramine
- buprenorphine
- bupropion
- buspirone
- busulfan
- butabarbital
- butalbital
- butorphanol
C
- canagliflozin
- candida albicans extract
- cannabidiol
- cannabis
- carbachol ophthalmic
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- ceritinib
- cetirizine
- charcoal
- chlophedianol
- chloral hydrate
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chlorphenesin
- chlorpromazine
- chlorpropamide
- chlorzoxazone
- cholestyramine
- cimetidine
- ciprofloxacin
- citalopram
- clemastine
- clidinium
- clobazam
- clofarabine
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- cobicistat
- cocaine nasal
- cocaine topical
- coccidioidin skin test
- codeine
- colchicine
- cyclizine
- cyclobenzaprine
- cyproheptadine
D
- daclizumab
- dacomitinib
- dantrolene
- dapagliflozin
- dapsone
- dapsone topical
- darifenacin
- deferasirox
- demecarium bromide ophthalmic
- deserpidine
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexchlorpheniramine
- dexfenfluramine
- dexmedetomidine
- dexmethylphenidate
- dextroamphetamine
- dextromethorphan
- dezocine
- diazepam
- dicumarol
- dicyclomine
- diethylpropion
- diflunisal
- digitoxin
- digoxin
- dihydroergotamine
- dimenhydrinate
- diphenhydramine
- dipyridamole
- disopyramide
- disulfiram
- divalproex sodium
- dobutamine
- donepezil
- dopamine
- doxapram
- doxepin
- doxepin topical
- doxylamine
- dronabinol
- dronedarone
- droperidol
- droxidopa
- dulaglutide
- duloxetine
- duvelisib
E
- echothiophate iodide ophthalmic
- efavirenz
- eliglustat
- eluxadoline
- empagliflozin
- enoxacin
- entacapone
- ephedrine
- epinephrine
- epirubicin
- epoprostenol
- ergonovine
- ergotamine
- ertugliflozin
- escitalopram
- esketamine
- eslicarbazepine
- estazolam
- eszopiclone
- ethanol
- ethchlorvynol
- ethinyl estradiol
- ethosuximide
- ethotoin
- evening primrose
- exenatide
- ezogabine
F
- felbamate
- fenfluramine
- fenoldopam
- fentanyl
- fesoterodine
- flavoxate
- flibanserin
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- formoterol
- fosphenytoin
- furazolidone
G
- galantamine
- ginkgo
- glimepiride
- glipizide
- glyburide
- glycerol phenylbutyrate
- glycopyrrolate
- glycopyrronium topical
- grepafloxacin
- guanadrel
- guanethidine
H
- halazepam
- haloperidol
- heroin
- histamine phosphate
- histoplasmin
- hyaluronidase
- hydrocodone
- hydromorphone
- hydroxyprogesterone
- hydroxyzine
- hyoscyamine
I
- idelalisib
- ifosfamide
- iloperidone
- iloprost
- imatinib
- imipramine
- incobotulinumtoxinA
- indacaterol
- indomethacin
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- interferon beta-1a
- interferon beta-1b
- iobenguane I 123
- iobenguane I 131
- ioflupane I 123
- iohexol
- iopamidol
- ipratropium
- ipratropium nasal
- isocarboxazid
- isoetharine
- isoflurophate ophthalmic
- isoniazid
- isoproterenol
K
L
- lamotrigine
- leflunomide
- levalbuterol
- levetiracetam
- levocetirizine
- levodopa
- levomethadyl acetate
- levomilnacipran
- levorphanol
- levothyroxine
- linagliptin
- lindane topical
- linezolid
- liraglutide
- lisdexamfetamine
- lithium
- lixisenatide
- lofexidine
- lomitapide
- loperamide
- lorazepam
- lorcaserin
- loxapine
- lurasidone
M
- ma huang
- maprotiline
- mazindol
- mecamylamine
- meclizine
- melatonin
- memantine
- mepenzolate
- meperidine
- mephentermine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaproterenol
- metaraminol
- metaxalone
- metformin
- methadone
- methamphetamine
- methdilazine
- methocarbamol
- methohexital
- methotrexate
- methotrimeprazine
- methoxamine
- methscopolamine
- methsuximide
- methyldopa
- methylene blue
- methylergonovine
- methylphenidate
- methysergide maleate
- metoclopramide
- metrizamide
- metyrosine
- mibefradil
- midazolam
- midodrine
- miglitol
- milnacipran
- mipomersen
- mirabegron
- mirtazapine
- molindone
- morphine
- morphine liposomal
- mumps skin test antigen
N
- nabilone
- nalbuphine
- nalidixic acid
- naltrexone
- nateglinide
- nefazodone
- nicotine
- nilotinib
- norepinephrine
- norfloxacin
- nortriptyline
O
- obeticholic acid
- olanzapine
- olaparib
- olodaterol
- olopatadine nasal
- onabotulinumtoxinA
- opium
- orphenadrine
- osimertinib
- ospemifene
- oxazepam
- oxcarbazepine
- oxybutynin
- oxycodone
- oxymorphone
- oxytocin
P
- paliperidone
- panobinostat
- paraldehyde
- paramethadione
- paroxetine
- peginterferon beta-1a
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perphenazine
- phenacemide
- phendimetrazine
- phenelzine
- phenindamine
- phenobarbital
- phensuximide
- phentermine
- phenylephrine
- phenytoin
- physostigmine
- physostigmine ophthalmic
- pilocarpine ophthalmic
- pimozide
- pioglitazone
- pirbuterol
- polyethylene glycol 3350 with electrolytes
- potassium chloride
- potassium citrate
- pramipexole
- pramlintide
- pregabalin
- prilocaine
- primidone
- probenecid
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propantheline
- propiomazine
- propoxyphene
- propranolol
- protriptyline
- pseudoephedrine
- pyrilamine
Q
R
- racepinephrine
- ramelteon
- ranitidine
- ranitidine bismuth citrate
- ranolazine
- rasagiline
- rauwolfia serpentina
- regadenoson
- remifentanil
- repaglinide
- reserpine
- revefenacin
- rifampin
- riluzole
- rimabotulinumtoxinB
- risperidone
- ritodrine
- rivastigmine
- rolapitant
- ropinirole
- ropivacaine
- rosiglitazone
- rotigotine
- rucaparib
- rufinamide
S
- safinamide
- salmeterol
- saxagliptin
- scopolamine
- secobarbital
- selegiline
- selexipag
- semaglutide
- sertraline
- sibutramine
- sitagliptin
- skin test antigens, multiple
- sodium iodide i-123
- sodium iodide-i-131
- sodium nitrite
- sodium oxybate
- sodium salicylate
- solifenacin
- st. john's wort
- stiripentol
- sufentanil
- sulfinpyrazone
- suvorexant
T
- tacrine
- tapentadol
- tasimelteon
- temazepam
- terbinafine
- terbutaline
- teriflunomide
- tetrabenazine
- thalidomide
- theophylline
- thiabendazole
- thiethylperazine
- thioguanine
- thiopental
- thioridazine
- thiothixene
- thyroid desiccated
- tiagabine
- timolol ophthalmic
- tiotropium
- tizanidine
- tolazamide
- tolbutamide
- tolcapone
- tolterodine
- topiramate
- topotecan
- trabectedin
- tramadol
- tranylcypromine
- trazodone
- treprostinil
- triazolam
- trichophyton skin test
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- troglitazone
- trospium
- trovafloxacin
- tuberculin purified protein derivative
U
V
W
Z
Acetaminophen / caffeine / chlorpheniramine / phenylpropanolamine alcohol/food interactions
There are 7 alcohol/food interactions with acetaminophen / caffeine / chlorpheniramine / phenylpropanolamine
Acetaminophen / caffeine / chlorpheniramine / phenylpropanolamine disease interactions
There are 21 disease interactions with acetaminophen / caffeine / chlorpheniramine / phenylpropanolamine which include:
- alcoholism
- liver disease
- cardiac disease
- hypertension
- liver disease
- PUD
- cardiovascular disease
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- cardiotoxicity
- psychiatric disorders
- renal dysfunction
- seizure disorders
- GERD
- psychosis
- BPH
- diabetes
- glaucoma
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
