Zoster Vaccine, Recombinant Dosage

Medically reviewed by Drugs.com. Last updated on Jan 1, 2025.

Usual Adult Dose for Varicella-Zoster - Prophylaxis

0.5 mL intramuscularly

• Administer two doses, with the second dose given 2 to 6 months after the first dose

Comments:

• This drug is not indicated for prevention of primary varicella infection (chickenpox).

Uses: Prevention of herpes zoster (shingles) in:

• Adults aged 50 years and older
• Adults aged 18 years and older at increased risk of herpes zoster (HZ) due to immunodeficiency or immunosuppression from disease or therapy

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Severe allergic reaction (e.g. anaphylaxis) to any of the ingredients or after a previous dose of this vaccine

Safety and efficacy have not been established in patients younger than 18 years.

To report suspected adverse reactions, contact the Vaccine Adverse Event Reporting System (VAERS) at: https://vaers.hhs.gov

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• For intramuscularly administration only.
• The preferred administration site is the deltoid region of the upper arm.

Storage requirements:

• Refrigerate; do not freeze
• Protect from light
• Discard if either component has been frozen.

Reconstitution/preparation techniques:

• Use only the diluent provided.
• Reconstituted product should be an opalescent, colorless to pale brownish liquid.
• Discard if particulate matter or discoloration are present after reconstitution.
• Administer immediately after reconstitution, or refrigerate between 36 and 46F and use within 6 hours.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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