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Teprotumumab Dosage

Medically reviewed by Last updated on Feb 21, 2023.

Applies to the following strengths: trbw 500 mg

Usual Adult Dose for Graves' Ophthalmopathy

Initial dose: 10 mg/kg intravenously
Maintenance dose: 20 mg/kg intravenously every 3 weeks for 7 additional infusions

Use: Treatment of thyroid eye disease

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available



Safety and efficacy have not been established in patients younger than 18 years.
This drug is not recommended for use in children.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:

  • Administer diluted solution over 90 minutes for the first 2 infusions; if well tolerated may reduce infusion time to 60 minutes for remaining infusions (if not well tolerated, continue 90 minute infusions).
  • Do not administer via intravenous push or bolus.

Storage requirements:
  • Refrigerate; do not freeze.
  • Protect from light.

Reconstitution/preparation techniques: The manufacturer product information should be consulted.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.