Penbraya Dosage

Step 1. Attachment of the vial adapter to the vial.

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Remove the flip top cap from the vial of Lyophilized MenACWY Component.

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Peel off the top cover from the vial adapter packaging.

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While keeping the vial adapter in its packaging, center the adapter over the vial’s stopper and attach to the vial with a straight downward push.

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Remove the packaging.

Step 2. Resuspension of the MenB Component.

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Shake the syringe containing the MenB Component vigorously to obtain a white homogenous suspension. Do not use if the contents cannot be resuspended.

Step 3. Connection of the syringe containing the MenB Component to the vial adapter.

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Hold the syringe by the Luer lock adapter.

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Twist to remove the syringe cap.

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Connect the syringe to the vial adapter by turning the Luer lock.

Step 4. Reconstitution of the Lyophilized MenACWY Component with the MenB Component to form PENBRAYA.

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Inject the entire contents of the syringe into the vial.

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Hold the plunger rod down and gently swirl the vial until the powder is completely dissolved (less than 1 minute).

Step 5. Withdrawal of PENBRAYA.

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Invert the vial completely and slowly withdraw the entire contents into the syringe for an approximately 0.5 mL dose of PENBRAYA.

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Twist to disconnect the syringe from the vial adapter.

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Attach a sterile needle suitable for intramuscular injection.