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Magnesium Gluconate Dosage

Medically reviewed by Last updated on Aug 11, 2023.

Applies to the following strengths: 500 mg; 1000 mg/5 mL; 65 mg/mL; 250 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Dietary Supplement

500 to 1000 mg magnesium gluconate (27 to 54 mg elemental magnesium) orally once a day.

Usual Pediatric Dose for Dietary Supplement

Recommended dietary intake (RDA) for magnesium:
Birth to 6 months: 30 mg (adequate intake)
7 to 12 months: 75 mg (adequate intake)
1 to 3 years: 80 mg
4 to 8 years: 130 mg
9 to 13 years: 240 mg
14 to 18 years, male: 410 mg
14 to 18 years, female: 360 mg

Tolerable upper intake level (UL) for supplemental magnesium:
1 to 3 years: 65 mg
4 to 8 years: 110 mg
9 to 18 years: 350 mg


  • Magnesium gluconate contains 5% elemental magnesium

Renal Dose Adjustments

Use with caution.

  • Magnesium elimination is decreased in renal impairment.
  • Digestive magnesium absorption is normal or decreased in renal impairment.

Liver Dose Adjustments

Data not available


Dose adjustment(s) may be required; however, no specific guidelines have been suggested. Caution is recommended.

  • Effects are similar in both hemodialysis and peritoneal dialysis.
  • Hypermagnesemia is common with creatinine clearance under 10 mL/min.
  • Mild hypermagnesemia is common with a dialysate magnesium of 0.75 mmol/L
  • Serum magnesium was normal to low with a dialysate magnesium between 0.2 and 0.25 mmol/L.
  • Ionized serum, ionized mononuclear and red blood cell measurements are not useful for hypermagnesemia detection.

Other Comments

Administration advice:

  • Take with food to prevent side effects.
  • Long acting formulations should not be crushed or chewed.
  • If a dose is missed, take it as soon as remembered, unless it's almost time for the next dose, in which case it should be skipped. Do not double up doses.

Patient advice:
  • Notify your doctor if you experience side effects that are severe or don't go away, such as diarrhea and stomach upset.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.