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Magnesium Gluconate Dosage

Medically reviewed on January 10, 2018.

Applies to the following strengths: 500 mg; 1000 mg/5 mL; 65 mg/mL; 250 mg

Usual Adult Dose for Hypomagnesemia

500 to 1000 mg magnesium gluconate (27 to 54 mg elemental magnesium) orally 3 times a day.

Usual Adult Dose for Dietary Supplement

500 to 1000 mg magnesium gluconate (27 to 54 mg elemental magnesium) orally once a day.

Usual Pediatric Dose for Hypomagnesemia

10 to 20 mg/kg of elemental magnesium per dose orally 4 times a day. Use magnesium gluconate oral liquid preparations for more accurate measurement of dose.

Renal Dose Adjustments

Do not use without physician supervision in patients with renal impairment due to increased risk of hypermagnesemia. The use of magnesium salts are generally contraindicated in patients with severe renal dysfunction.

Liver Dose Adjustments

Data not available

Dose Adjustments

May increase by 500 to 1,000 mg/day (27 to 54 mg elemental magnesium) in order to achieve a normal serum magnesium level. Daily doses > 1,000 mg (54 mg elemental magnesium) should be given in 2 to 3 divided doses.


Because magnesium is primarily eliminated by the kidney, there is significant risk of hypermagnesemia in patients with renal dysfunction.


Data not available; however, use of magnesium salts is generally contraindicated in renal failure.

Other Comments

Magnesium supplements are often used with "low normal" serum magnesium levels in patients predisposed to hypomagnesemia (e.g., patients on diuretics).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.