Lysodren Dosage
Generic name: mitotane 500mg
Dosage form: tablet
Medically reviewed by Drugs.com. Last updated on Jan 6, 2020.
Recommended Dose
The recommended initial dose of LYSODREN is 2 g to 6 g orally, in three or four divided doses per day. Increase doses incrementally to achieve a blood concentration of 14 to 20 mg/L, or as tolerated.
LYSODREN is a cytotoxic drug. Follow applicable special handling and disposal procedures.
Dose Modifications
Adrenal Crisis in the Setting of Shock or Severe Trauma
Discontinue LYSODREN until recovery [see Warnings and Precautions (5.1)].
Central Nervous System (CNS) Toxicity
Discontinue LYSODREN until symptoms resolve. Seven to 10 days after symptoms resolve, restart at a lower dose (for example, decrease by 500-1000 mg) [see Warnings and Precautions (5.2)].
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Lysodren (mitotane)
- Side Effects
- During Pregnancy
- Drug Images
- Drug Interactions
- Compare Alternatives
- Pricing & Coupons
- En Español
- Drug class: miscellaneous antineoplastics
